對(duì)近10年來中外期刊有關(guān)虎杖Polygonum cuspidatum的研究成果進(jìn)行了檢索,對(duì)從虎杖中分離并鑒定的化學(xué)成分及藥理活性研究進(jìn)展進(jìn)行總結(jié)。虎杖中主要含有蒽醌類、二苯乙烯類、黃酮類、香豆素類以及一些脂肪酸類化合物,具有多種藥理作用,包括抗炎、抗病毒、抗菌、調(diào)血脂、抗血栓、改變血流變、擴(kuò)張血管、保護(hù)心肌、抗氧化、抗腫瘤,改善阿爾茨海默病及預(yù)防艾滋病等。多年來對(duì)虎杖的研究成果證明了其應(yīng)用前景和開發(fā)價(jià)值,為更好地利用該資源提供依據(jù)。

In recent 10 years, the lectures for studies on the roots and rhizomes of Polygonum cuspidatum in both Chinese and foreign periodicals have been retrieved, the chemical constituents isolated and identified from the roots and rhizomes of P. cuspidatum and their pharmacological progress have been analyzed and summarized. There are main anthraquinones, stilbene, flavonoids, coumarins, and some fatty compounds in the roots and rhizomes of P. cuspidatum, which have a variety of pharmacological effects, including anti-inflammation, antivirus, antibiosis, regulation of blood lipid, antithrombosis, change of blood rheology, dilation of blood vessels, protection of myocardium, anti-oxidation, anticancer, improvement of Alzheimer's disease, prevention of AIDS, and so on. The studies on the roots and rhizomes of P. cuspidatum over the years have proven its value and development prospects, and provide the information for the further development and utilization of the roots and rhizomes of P. cuspidatum.

國家自然科學(xué)基金(2711001002001)