目的 對國產(chǎn)廠家與原研廠家生產(chǎn)的卡托普利片的質(zhì)量進(jìn)行比對研究。方法 按照《中國藥典》第一增補(bǔ)本的方法對不同廠家的卡托普利片進(jìn)行實驗，測定二硫化物、溶出曲線、含量測定等項目，綜合評定產(chǎn)品質(zhì)量。結(jié)果 各廠家質(zhì)量均符合標(biāo)準(zhǔn)規(guī)定。國產(chǎn)廠家在二硫化物、溶出曲線等項目與原研廠家存在差異性。結(jié)論 國內(nèi)部分廠家與原研廠家質(zhì)量存在差異，建議提高工藝水平，提高藥品質(zhì)量。

Objective To research the quality of Captopril Tablets of domestic manufacturers and the original manufacturer. Methods Captopril-disuphide, dissolution cures and content was determined according to CP 2010 the first enlarged edition of different manufacturers, for comprehensive evaluation of the quality of the products. Results The quality of each manufacturer was promising. There are differences in Captopril-disuphide and dissolution cures projects between the original manufacturer and domestic manufacturers. Conclusion Part of domestic manufacturers' quality was different with the original manufacturer, suggest to raise the level of technology improve the quality of medicines.