目的 研究丁苯酞對老年急性腦梗死的療效及對血清尿酸、C反應(yīng)蛋白和血液流變學(xué)的影響。方法 選擇2015年1月-2015年12月在西安市第一醫(yī)院進(jìn)行診治的老年急性腦梗死患者86例，隨機(jī)分為兩組，對照組采用常規(guī)急性腦梗死對癥治療，觀察組加用丁苯酞膠囊。觀察兩組的美國國立衛(wèi)生研究院卒中量表（NIHSS）評分、Barthel指數(shù)和療效，檢測并比較治療前后兩組患者血清尿酸、C反應(yīng)蛋白、血小板聚集率和血黏稠度。結(jié)果 觀察組的有效率為90.70%，明顯高于對照組的72.09%（P<0.05）；治療后兩組的NIHSS評分、血清尿酸和C反應(yīng)蛋白水平、血小板聚集率和血黏稠度均明顯降低，Barthel指數(shù)明顯升高（P<0.05），且觀察組的變化較對照組更為明顯（P<0.05）。結(jié)論 丁苯酞對老年急性腦梗死患者的療效顯著，能降低患者的血清尿酸、C反應(yīng)蛋白水平和神經(jīng)功能缺損程度，改善其血液流變學(xué)狀態(tài)和生活自理活動能力，具有腦保護(hù)作用。

Objective To investigate the efficacy of butylphthalide on elderly patients with acute cerebral infarction and its effect on serum uric acid, c-reactive protein, and hemorheology. Methods Elderly patients (86 cases) with acute cerebral infarction in Xi'an No.1 Hospital from January 2015 to December 2015 were randomly divided into two groups. The control group was treated with conventional symptomatic treatment of acute cerebral infarction, observation group added with butylphthalide soft capsules. The NIHSS score and efficacy of the two groups, the serum uric acid, c-reactive protein, and the change of hemorheology before and after treatment were compared. Results The effective rate of observation group was 90.70%, significantly higher than that of control group 72.09% (P<0.05); The NIHSS score, serum uric acid and c-reactive protein levels, blood viscosity and platelet aggregation rate of two groups after treatment were significantly lower (P<0.05), the Barthel index were significantly increased (P<0.05), and the change of observation group were more significant (P<0.05). Conclusion Butylphthalide has high curative effect on elderly patients with acute cerebral infarction, can reduce the level of serum uric acid, c-reactive protein and the degree of nerve function defect, improve the hemorheology and life self-care activities ability, which can protect the brain.