目的 探討康柏西普眼內(nèi)注射對(duì)糖尿病性視網(wǎng)膜病變行玻璃體切割手術(shù)的影響。方法 選取100例糖尿病視網(wǎng)膜病變患者，按術(shù)前眼內(nèi)是否注射藥物分為兩組，注射組（49例）玻璃體切割術(shù)前7 d眼內(nèi)注射康柏西普，對(duì)照組（51例）單純行玻璃體切割術(shù)。通過(guò)觀察并記錄患者手術(shù)情況、預(yù)后情況、術(shù)前術(shù)后視力情況，評(píng)價(jià)康柏西普眼內(nèi)注射對(duì)糖尿病性視網(wǎng)膜病變行玻璃體切割手術(shù)的影響。結(jié)果 與對(duì)照組相比，注射組所需手術(shù)時(shí)間更短（P<0.05），注射組出血眼數(shù)6例，對(duì)照組出血眼數(shù)20例，注射組出血眼數(shù)明顯少于對(duì)照組（P<0.05）。此外，注射組術(shù)中電凝眼數(shù)、硅油使用眼數(shù)、醫(yī)源性裂孔眼數(shù)均明顯少于對(duì)照組（P<0.05）；術(shù)后隨訪1個(gè)月，注射組少量出血例數(shù)和大量活動(dòng)性出血例數(shù)均明顯少于對(duì)照組（P<0.05）；術(shù)前兩組視力相比，差異沒(méi)有統(tǒng)計(jì)學(xué)意義（P<0.05）。術(shù)后1個(gè)月，兩組視力均明顯提高且注射組視力明顯高于對(duì)照組（P<0.05）。結(jié)論 康柏西普眼內(nèi)注射有利于玻璃體切割手術(shù)的進(jìn)行，可降低手術(shù)難度，縮短手術(shù)時(shí)間，減少術(shù)中、術(shù)后出血癥狀，提高患者矯正視力。

Objective To discuss the influence of conbercept intraocular injection to vitrectomy on diabetic retinopathy. Methods patients (100 cases) with diabetic retinopathy were divided into two groups according to whether use intraocular injection drug or not. The injection group (49 cases) was given conbercept intraocular injection before vitrectomy. The control group (51 cases) was only given vitrectomy. The influence of conbercept intraocular injection to vitrectomy on diabetic retinopathy was evaluated by surgery, prognosis, visual acuity before and after surgery. Results The surgery time of the injection group was shorter than that of the control group (P<0.05). There were six bleeding cases in the injection group and 20 cases in the control group. The number of bleeding of injection group was shorter than that of the control group (P<0.05). In addition, the electric coagulation, silicone oil use, iatrogenic macular holes number of injection group was smaller than of that of the control group (P<0.05). During 1 month follow-up, the number of small bleeding and large bleeding cases of injection group was smaller than of the control group (P<0.05). There was no statistical significance on vision between two groups. After 1 month surgery, the vision of two groups were increased. And the vision of injection group was significantly higher than that of the control group (P<0.05). Conclusion In summary, conbercept intraocular injection could help vitrectomy. It could reduce the difficulty of surgery and shorten the surgery time. It could reduce the bleeding symptoms during and after surgery. It could improve the vision of patients.