目的 探究地奧司明和尼美舒利聯(lián)用治療膝關(guān)節(jié)創(chuàng)傷性滑膜炎的臨床療效。方法 選取解放軍第425醫(yī)院收治的符合診斷標(biāo)準(zhǔn)和本研究要求的患者60名，分為3組，聯(lián)合組、尼美舒利組、地奧司明組各20例，聯(lián)合組給予地奧司明和尼美舒利聯(lián)合治療，尼美舒利組予以尼美舒利治療，地奧司明組予以地奧司明治療，均以14 d為1療程。分別對(duì)治療前后各組進(jìn)行膝關(guān)節(jié)VAS、AKS評(píng)分、腫脹程度評(píng)級(jí)，并根據(jù)以上數(shù)據(jù)進(jìn)行療效判定。結(jié)果 經(jīng)過(guò)14 d治療后，3組患者治療后膝關(guān)節(jié)腫脹、疼痛程度均較前有不同程度改善，治療前后差異明顯（P<0.05），且聯(lián)合組的前后差異幅度更大（P<0.05），有效率更高。結(jié)論 地奧司明和尼美舒利分別對(duì)創(chuàng)傷性滑膜炎治療均有一定療效，但單獨(dú)使用不及兩者聯(lián)合治療療效顯著。聯(lián)合使用可更加明顯的緩解患者的疼痛，阻止病情進(jìn)展，減輕炎癥反應(yīng)，穩(wěn)定病情，達(dá)到滿意的治療效果。

Objective To observe the clinical curative effect of diosmin combined with nimesulide in treatment of drugs for the traumatic synovitis ofin knee joint. Methods Sixty patients the People's Liberation Army 425 Hospital diagnosis standard and the requirements in this study were averagely and randomly divided into combination group, nimesulide group and diosmin group, the patients in combination group were given diosmin and nimesulide treatment, the patients in nimesulide group were given nimesulide treatment, diosmin group were given diosmin treatment. The course of treatment was 14 d. Then score knee joint VAS, AKS rating, and swelling degree in each group before and after the treatment. Results After treatment, the patients with knee joint swelling, pain degree are improved, the difference before and after treatment has statistical significance (P<0.05), meanwhile differences in the combination group were larger than the other two groups (P<0.05). Conclusion The drugs of nimesulide and diosmin for the treatment of traumatic synovitis respectively have certain effect, but the combined treatment curative effect is remarkable than used alone. Combination medication can be more obviously relieving the pain of patients and prevent disease progression, reduce inflammation which achieved a satisfactory therapeutic effect.