目的 探討克林霉素注射液聯(lián)合保婦康栓對慢性宮頸炎伴高危型人乳頭瘤病毒（hr-HPV）感染患者的療效分析。方法 選取100例慢性宮頸炎伴hr-HPV感染患者，隨機分為兩組，對照組（49例）給予保婦康栓，觀察組（51例）給予克林霉素注射液聯(lián)合保婦康栓，觀察并記錄兩組療效、HPV轉(zhuǎn)陰率、治療前后炎性因子水平、治療期間兩組不良反應(yīng)情況，評價保婦康栓聯(lián)合克林霉素注射液對慢性宮頸炎伴hr-HPV感染患者的治療效果。結(jié)果 治療后，觀察組有效率為92.1%，對照組有效率為75.5%，觀察組有效率明顯高于對照組（P<0.05）；治療后，觀察組HPV轉(zhuǎn)陰率為90.2%，對照組為59.2%，觀察組治療后HPV轉(zhuǎn)陰率明顯高于對照組（P<0.05）。治療前，兩組超敏C反應(yīng)蛋白（hs-CRP）、白介素-6（IL-6）、腫瘤壞死因子-α（TNF-α）無統(tǒng)計學(xué)差異；治療后，兩組hs-CRP、IL-6、TNF-α均明顯下降，且觀察組hs-CRP、IL-6、TNF-α水平明顯低于對照組（P<0.05）；治療期間，兩組不良反應(yīng)率比較，差異無統(tǒng)計學(xué)意義。結(jié)論 克林霉素注射液聯(lián)合保婦康栓對慢性宮頸炎伴hr-HPV具有良好的治療作用，抗HPV效果好，能顯著控制炎癥因子，且安全性好，值得臨床推廣使用。

Objective To discuss the efficacy of Baofukang combined with clindamycin injection in treatment of chronic cervicitis patients with high-risk human papilloma virus infection (hr-HPV).Methods Totally 100 patients who had chronic cervicitis with hr-HPV were selected and divided into two groups randomly. The patients in control group (49 cases) were given Baofukang. The patients in observation group (51 cases) were given Baofukang combined with clindamycin injection. The efficacy of Baofukang combined with clindamycin injection in treatment of chronic cervicitis patients with hr-HPV was evaluated by efficacy, HPV negative rate, inflammatory factors before and after treatment and adverse reaction during treatment.Results After treatment, the effective rate of observation group was 92.1%, and the effective rate of control group was 75.5%, the effective rate of observation group was higher than that of control group (P<0.05). After treatment, the HPV negative rate in observation group was 90.2%, the control group was 59.2%, the HPV negative rate of observation group was higher than that of control group (P<0.05). Before treatment, there was no statistical significance on hs-CRP, IL-6, and TNF-α between two groups. After treatment, the hs-CRP, IL-6, and TNF-α were decreased in two groups (P<0.05). The hs-CRP, IL-6, and TNF-α of observation group were lower than those of control group (P<0.05). There was no statistical significance on adverse reaction between two groups.Conclusion Baofukang combined with clindamycin injection had a good therapeutic effect on chronic cervicitis with hr-HPV. It could inhibit HPV and inflammatory factors well. It was safe and worthy of clinical use.