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[摘要]
目的 探討復(fù)方樟柳堿聯(lián)合卵磷脂絡(luò)合碘片對中心性漿液性脈絡(luò)膜視網(wǎng)膜病變的療效。方法 選取60例中心性漿液性脈絡(luò)膜視網(wǎng)膜病變患者,按隨機(jī)數(shù)字表法分為兩組,對照組(29例)口服卵磷脂絡(luò)合碘片1.5 mg/次,3次/d;觀察組在對照組基礎(chǔ)上靜脈推注復(fù)方樟柳堿注射液2 mL,1次/d,兩組均治療14 d。觀察并記錄兩組療效,視力水平,光敏感度及治療期間不良反應(yīng),評價(jià)復(fù)方樟柳堿聯(lián)合卵磷脂絡(luò)合碘片治療中心性漿液性脈絡(luò)膜視網(wǎng)膜病變的療效。結(jié)果 治療后,觀察組患者治療有效率為93.5%,對照組患者治療有效率為79.3%,觀察組有效率明顯高于對照組(P<0.05);治療前兩組視力水平無統(tǒng)計(jì)學(xué)差異,治療后兩組時間視力水平均明顯提高且觀察組視力更好(P<0.05);治療前,兩組光敏感度無統(tǒng)計(jì)學(xué)差異,治療后2、4周,兩組光敏感度均明顯提高,且觀察組光敏感度值更高(P<0.05)。治療期間,兩組不良反應(yīng)率無統(tǒng)計(jì)學(xué)差異。結(jié)論 復(fù)方樟柳堿聯(lián)合卵磷脂絡(luò)合碘片對中心性漿液脈絡(luò)膜視網(wǎng)膜病變具有較好療效,能夠提高患者視力,改善眼部光敏感度,用藥具有安全性,值得臨床推廣使用。
[Key word]
[Abstract]
Objective To discuss the efficacy of Compound Anisodine Injection combined with Iodized Lecithin Tablets in treatment of central serous chorioretinopathy.Methods Totally 60 patients with CSC were selected, and divided into two groups randomly. The patients in control group (29 cases) were given Iodized Lecithin Tablets. The patients in observation group (31 cases) were given Iodized Lecithin Tablets and Compound Anisodine Injection. The efficacy of Compound Anisodine Injection combined with Iodized Lecithin Tablets in treatment of central serous chorioretinopathy was evaluated by efficacy, visual acuity, light sensitivity, and adverse reaction during treatment.Results After treatment, the effective rates of observation and control groups were 93.5% and 79.3%, and the observation group was significantly higher than control group (P<0.05). There were no statistical significance on visual acuity between two groups. After treatment, rhe visual acuity of two groups was increased and the visual acuity in the observation group was better (P<0.05). Before treatment, there were no statistical significance on light sensitivity between two groups. After 2 and 4 weeks treatment, the light sensitivity of two groups were increased and the light sensitivity in the observation group was higher (P<0.05). During treatment, there was no statistical significance on adverse reaction between two groups.Conclusion Compound Anisodine Injection combined with Iodized Lecithin Tablets has a curative effect on central serous chorioretinopathy. It could increase the visual acuity and improve the light sensitivity of eyes with good security. It is worthy of clinical use.
[中圖分類號]
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