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[摘要]
目的 探討鹽酸氨溴索霧化吸入治療新生兒肺炎的療效。方法 選取80例肺炎患兒,按隨機(jī)數(shù)字表法分為兩組,對(duì)照組(39例)常規(guī)抗感染、止咳等綜合治療,觀察組(41例)在對(duì)照組治療基礎(chǔ)上,給予鹽酸氨溴索霧化吸入,觀察并記錄兩組患者療效、臨床癥狀消失時(shí)間、紅細(xì)胞壓積、血液黏稠度及治療期間不良反應(yīng)情況,評(píng)價(jià)鹽酸氨溴索霧化吸入對(duì)新生兒肺炎的療效。結(jié)果 治療后觀察組有效率高于對(duì)照組(P<0.05),觀察組38例患兒,對(duì)照組28例患兒治療后咳嗽、憋喘減輕,痰量減少;鹽酸氨溴索霧化吸入治療后,觀察組患兒咳嗽、肺部濕啰音消失時(shí)間及平均住院時(shí)間明顯縮短(P<0.05);治療后觀察組患者紅細(xì)胞壓積、血液黏稠度均低于對(duì)照組(P<0.05);治療期間兩組不良反應(yīng)率無統(tǒng)計(jì)學(xué)差異。結(jié)論 鹽酸氨溴索霧化吸入對(duì)新生兒肺炎具有較好的治療效果,能迅速改善肺炎癥狀,降低血液黏稠度,用藥安全,值得臨床推廣使用。
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[Abstract]
Objective To discuss the efficacy of ambroxol hydrochloride inhalation in treatment of infantile pneumonia.Methods Totally 80 pneumonia infants were selected and randomly divided into two groups. The control group (39 cases) were given anti-infection, cough-relieved, and other treatment. The observation group (41 cases) were given ambroxol hydrochloride inhalation on the basis of control group treatment. The efficacy of ambroxol hydrochloride inhalation in treatment of infantile pneumonia was evaluated by efficacy, clinical symptoms disappearing time, red blood cell hematocrit, blood viscosity, and adverse reaction during treatment.Results After treatment, the effective rate of observation group was higher than that of control group (P<0.05). There were 38 infants in observation group and 28 infants in control group with cough and dyspnea alleviated and phlegm reduced. After atomizing inhalation of ambroxol hydrochloride, the cough, pulmonary rales disappearing time and hospitalization time were significantly shortened (P<0.05). After treatment, the red blood cell hematocrit and blood viscosity of observation group was lower than that of control group (P<0.05). During treatment, there was no statistical significance on adverse reaction between two groups.Conclusion Ambroxol hydrochloride inhalation has a good curative effect on infantile pneumonia. It could improve the symptoms of pneumonia and reduce blood viscosity with good safety, which is worthy of clinical use.
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