目的 研究血栓通注射液聯(lián)合單唾液酸四己糖神經(jīng)節(jié)苷脂對腦梗死的治療效果。方法 選擇2013年1月-2015年12月在新疆維吾爾自治區(qū)職業(yè)病醫(yī)院進(jìn)行診治的腦梗死患者100例，隨機(jī)分為兩組。對照組靜脈滴注血栓通注射液，研究組靜脈滴注血栓通注射液及單唾液酸四己糖神經(jīng)節(jié)苷脂，兩組均治療2周。比較兩組的治療效果，血清白介素-6、C反應(yīng)蛋白水平，NIHSS評分、Barthel指數(shù)以及血液流變學(xué)變化。結(jié)果 研究組的有效率為92.00%，明顯高于對照組的70.00%，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后兩組的血清白介素-6和C反應(yīng)蛋白水平均明顯降低，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且研究組血清白介素-6和C反應(yīng)蛋白水平明顯低于對照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后兩組的NIHSS評分明顯降低，Barthel指數(shù)明顯升高，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且研究組明顯優(yōu)于對照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后兩組的血小板聚集率和血黏稠度均明顯降低，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且研究組血小板聚集率和血黏稠度明顯低于對照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 血栓通注射液聯(lián)合單唾液酸四己糖神經(jīng)節(jié)苷脂具有顯著的治療效果，可以明顯改善腦梗死患者的炎癥因子水平、神經(jīng)功能、日常生活能力和血液流變學(xué)。

Objective To investigate the clinical effect of Xueshuantong Injection combined with Sodium Monosialotetrahexosylganglioside Injection on cerebral infarction. Methods Selected 100 cases of patients with cerebral infarction who were treated in Occupational Disease Hospital of Xinjiang Uygur Autonomous Region from January 2013 to December 2015, divided into two groups randomly. The observation group was treated with Xueshuantong Injection combined with Sodium Monosialotetrahexosylganglioside Injection, control group was treated with Xueshuantong Injection. The therapeutic effect, IL-6, C reactive protein level, NIHSS score, Barthel index and hemorheology were compared. Results The effective rate of observation group was 92.00%, significantly higher than the control group 70.00%, the difference was statistically significant (P< 0.05). The level of serum IL-6 and C reactive protein were significantly decreased (P< 0.05), and the observation group decreased more obviously, the difference was statistically significant(P< 0.05). After treatment, NIHSS score of two groups decreased significantly, and Barthel index increased significantly (P< 0.05), and the study group was significantly better than the control group,the difference was statistically significant (P< 0.05). After treatment, platelet aggregation and blood viscosity were decreased significantly (P< 0.05), and the observation group decreased more obviously, the difference was statistically significant (P< 0.05). Conclusion Xueshuantong Injection combined with Sodium Monosialotetrahexosylganglioside Injection has significant therapeutic effect, can significantly improve the level of inflammatory factors, neural function, ability of daily life and blood rheology in patients with cerebral infarction.