目的 系統(tǒng)評價中藥輔助抗菌藥治療小兒腸系膜淋巴結(jié)炎的療效。方法 檢索1980-2016年中國期刊全文數(shù)據(jù)庫（CNKI）、萬方數(shù)字化期刊全文庫、中文科技期刊全文數(shù)據(jù)庫（VIP）、PubMed、Medline數(shù)據(jù)庫中關(guān)于中藥輔助抗菌藥治療小兒腸系膜淋巴結(jié)炎的隨機(jī)對照研究（RCT），依據(jù)納入和排除標(biāo)準(zhǔn)篩選文獻(xiàn)，采用Jadad評分進(jìn)行評價，運(yùn)用RevMan 5.3軟件進(jìn)行Meta分析。結(jié)果 共納入34篇臨床RCT，3 504例患者。Meta分析結(jié)果顯示試驗組在有效率、治愈率、主要癥狀和體征緩解時間、腸系膜淋巴結(jié)恢復(fù)、復(fù)發(fā)率方面均優(yōu)于對照組，兩者差異具有統(tǒng)計學(xué)意義。結(jié)論 中藥輔助抗菌藥物治療小兒腸系膜淋巴結(jié)炎療效優(yōu)于單獨(dú)使用抗菌藥。

Objective To assess the effectiveness of Chinese materia medica(CMM) as adjuvant therapy of antibacterial for pediatric mesenteric lymphadenitis. Methods Retrieved RCTresearch of CMM as adjuvant therapy of antibacterial for pediatric mesenteric lymphadenitis from CNKI, Wanfang, VIP,PubMed, andMedline database from 1980 to 2016. Literatures were selected according to the inclusion and exclusion crteria, Jadad scores method was used to evaluate the literatures and meta-analysis was performed by RevMan 5.3. Results A total of 34 randomized controlled trials were included. Meta-analysis showed that the trial group was superior to the control group in terms of efficiency, cure rate, remission time of main symptoms, mesenteric lymph node recovery, and recurrence rate, there was statistical difference. Conclusions CMM as adjuvant therapy of antibacterial for pediatric mesenteric lymphadenitis is more effective than the use of antibacterial alone.

遼寧省科學(xué)技術(shù)計劃項目（2014226033）