目的 探討銀杏達(dá)莫與丹參川芎嗪注射液治療老年急性心肌梗死的臨床療效。方法 選取60例老年急性心肌梗死患者，隨機(jī)數(shù)字表法分為兩組，均給予常規(guī)治療，觀察組患者（30例）在此基礎(chǔ)上給予銀杏達(dá)莫注射液治療，對(duì)照組患者（30例）在此基礎(chǔ)上給予丹參川芎嗪注射液治療，根據(jù)療效，治療前后血液流變學(xué)指標(biāo)及治療期間不良反應(yīng)情況，評(píng)價(jià)銀杏達(dá)莫與丹參川芎嗪注射液治療老年急性心肌梗死的臨床療效。結(jié)果 觀察組治療有效率86.7%，對(duì)照組治療有效率90.0%，兩組治療急性心肌梗死的有效率差異無統(tǒng)計(jì)學(xué)意義。治療前，兩組血液黏度、紅細(xì)胞壓積、血小板聚集率相比，差異無統(tǒng)計(jì)學(xué)意義；治療后兩組血液黏度、紅細(xì)胞壓積和血小板聚集率均降低，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且觀察組紅細(xì)胞壓積和血小板聚集率低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05），但血液黏稠度治療后兩組沒有明顯差異。根據(jù)單個(gè)藥品的花費(fèi)成本以及治療有效率，計(jì)算成本/效果比，可知銀杏達(dá)莫注射液的成本/效果比值明顯小于丹參川芎嗪注射液，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療期間，兩組不良反應(yīng)率比較無明顯差異。結(jié)論 銀杏達(dá)莫與丹參川芎嗪注射液對(duì)老年急性心肌梗死均具有較好的治療效果，藥物安全性高，但銀杏達(dá)莫注射液在抑制血小板聚集、降低紅細(xì)胞壓積方面作用較強(qiáng)，成本/效果值較低。

Objective To discuss the efficacy of Ginkgo Leaf Extract and Dipyridamole Injection and Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in treatment of acute myocardial infarction. Methods 60 cases of acute myocardial infarction were randomly divided into two groups. They were treated with routine treatment. The observation group (30 cases) was treated with Ginkgo Leaf Extract and Dipyridamole Injection on the basis of routine treatment. The control group (30 cases) was treated with Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection on the basis of routine treatment. The efficacy of Ginkgo Leaf Extract and Dipyridamole Injection and Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in treatment of acute myocardial infarction was evaluated by the efficacy, hemorheology before and after treatment, adverse reaction during treatment. Results The effective rate of observation group was 86.7%. The effective rate of control group was 90.0%. There was no statistical significance on effective rate between two groups. Before treatment, there were no statistical significance on blood viscosity, hematocrit, platelet aggregation rate between two groups. After treatment, the blood viscosity, hematocrit, platelet aggregation rate were decreased in two groups (P<0.05). The observation group of hematocrit and platelet aggregation rate was lower than the control group (P<0.05). But the blood viscosity of two groups had no significant difference. According to the cost and the efficiency of single drug treatment, calculate the cost/effect ratio, the Ginkgo Leaf Extract and Dipyridamole Injection of cost/effect ratio was significantly less than that of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection (P<0.05). During treatment, there was no statistical significance on adverse reaction rate between two groups. Conclusion Ginkgo Leaf Extract and Dipyridamole Injection and Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection had a therapeutic effect on acute myocardial infarction with high safety. The Ginkgo Leaf Extract and Dipyridamole Injection could inhibit the platelet aggregation, reduce the hematocrit with low cost/effect value.