目的 對(duì)比分析阿托伐他汀、辛伐他汀、瑞舒伐他汀對(duì)高脂血癥的治療效果。方法 選擇2014年1月-2016年1月在商南縣醫(yī)院進(jìn)行診治的高脂血癥患者120例，隨機(jī)分為阿托伐他汀組、辛伐他汀組以及瑞舒伐他汀組，分別采用阿托伐他汀、辛伐他汀、瑞舒伐他汀治療，3組均治療8周。比較3組治療前、治療第4周和治療第8周的血脂水平，以及不良反應(yīng)發(fā)生情況。結(jié)果 3組治療第4周和治療第8周的血脂水平均明顯改善，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且瑞舒伐他汀組明顯優(yōu)于阿托伐他汀組和辛伐他汀組，組間比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。3組的不良反應(yīng)發(fā)生率相比無明顯差異。結(jié)論 阿托伐他汀、辛伐他汀和瑞舒伐他汀均可以有效改善高脂血癥患者的血脂水平，且瑞舒伐他汀的治療效果最佳。

Objective To compare the efficacy of atorvastatin, simvastatin and rosuvastatin in the treatment of hypercholesterolemia. Methods Selected 120 cases of patients with hypercholesterolemia who were treated in our hospital from January 2014 to December 2016, divided into atorvastatin group, simvastatin group and rosuvastatin group. The blood lipid levels and the incidence of adverse reactions were compared between the three groups before treatment, after treatment for fourth weeks and after treatment for eighth weeks. Results The serum lipid level were significantly improved in three groups after treatment (P<0.05), and rosuvastatin group was significantly better than atorvastatin group and simvastatin group (P<0.05); the incidence of adverse reactions of the three groups showed no significant difference. Conclusion Atorvastatin, simvastatin and rosuvastatin can effectively improve the blood lipid levels in patients with hypercholesterolemia, and the effect of rosuvastatin is the best.