目的 對比分析前列地爾注射液與復(fù)方丹參注射液治療糖尿病足的治療效果。方法 選擇2012年1月-2016年12月在北京市昌平區(qū)中西醫(yī)結(jié)合醫(yī)院進(jìn)行診治的糖尿病足患者210例，隨機(jī)分為3組，每組各70例。A組單獨(dú)采用前列地爾注射液治療，B組單獨(dú)采用復(fù)方丹參注射液治療，C組采用前列地爾注射液與復(fù)方丹參注射液中西醫(yī)結(jié)合治療，比較3組的臨床治療效果，治療前后的血脂水平、尿素氮、肌酐、β2微球蛋白以及尿微量白蛋白水平。結(jié)果 C組的有效率為92.86%（65/70），明顯高于A組和B組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療后3組的三酰甘油（TG）、總膽固醇（TC）和低密度脂蛋白膽固醇（LDL-C）水平均明顯降低，高密度脂蛋白膽固醇（HDL-C）水平均明顯升高，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且C組與其他兩組比較變化更為明顯，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后3組的尿素氮、肌酐、β2微球蛋白以及尿微量白蛋白水平均明顯降低，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且C組與其他兩組比較降低更為明顯，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 前列地爾注射液與復(fù)方丹參注射液中西醫(yī)結(jié)合治療對糖尿病足具有顯著的臨床治療效果，安全有效，值得應(yīng)用推廣。

Objective To study the therapeutic effects of Alprostadil Injection and Composite Salvia Injection on diabetic foot. Methods Selected 210 cases of patients with diabetic foot who were treated in our hospital from January 2012 to December 2016, divided into three groups randomly. The group A was treated with Alprostadil Injection, group B was treated with Composite Salvia Injection, the group C was treated with Alprostadil Injection and Composite Salvia Injection. The clinical therapeutic effects of the three groups were compared, and the levels of blood lipid, urea nitrogen, creatinine, beta-globulin and urinary microalbumin before and after treatment were compared. Results After treatment, the effective rate of the group C was 92.86% (65/70), significantly higher than that of the group A and B (P < 0.05). After treatment, the levels of TG, TC and LDL-C in the three groups were significantly lower than before treatment (P < 0.05), HDL-C levels were significantly higher than before treatment (P < 0.05), and the group C was more significant (P < 0.05). After treatment, the levels of urea nitrogen, creatinine, beta 2 and urinary microalbumin were significantly decreased in the three groups than before (P < 0.05), and the group C was more significant (P < 0.05). Conclusion The effect of Alprostadil Injection and Composite Salvia Injection on diabetic foot is better, which is safe and effective.