目的 調(diào)查腫瘤患者使用脂肪乳注射液的用藥情況，為合理用藥提供參考。方法 采用回顧分析法，從鄭州大學(xué)附屬腫瘤醫(yī)院2016年1-12月所有使用脂肪乳注射液腫瘤患者的病例中隨機(jī)抽取1500份，根據(jù)相關(guān)標(biāo)準(zhǔn)就脂肪乳的適應(yīng)證、藥物選擇、配伍合理性、給藥途徑等方面進(jìn)行專項(xiàng)點(diǎn)評。結(jié)果 調(diào)查的1 500例腫瘤患者中，以圍手術(shù)期患者居多，占68.2%。528例用藥不合理，占35.2%；其中，適應(yīng)癥不適宜占16.1%，藥物選擇不適宜占44.5%，用法用量不適宜占50.6%，配伍禁忌占18.3%。結(jié)論 該院脂肪乳注射液臨床應(yīng)用不合理現(xiàn)象較為明顯，需采取措施強(qiáng)化該類藥品的規(guī)范使用。

Objective To evaluate the clinical application of Fat Emulsion Injection in tumor patients and provide references for rational drug use. Methods A total of 1500 cases administered with Fat Emulsion Injection during January and December 2016 in Affiliated Cancer Hospital of Zhengzhou University were collected randomly and evaluated with the relevant standards. Results From the investigation of a total of 1 500 patients with cancer, fat Emulsion Injection was mainly used in the surgery department (68.2%). Of 1500 cases, unreasonable medical records accounted for 35.2%; inappropriate indication accounted for 16.1%, inappropriate selection of drugs accounted for 44.5%, incorrect dosage accounted for 50.6%, and incompatibility accounted for 18.3%. Conclusion Unreasonable use of Fat Emulsion Injection in the hospital is prevalent, therefore, measures should be taken to strengthen the standard use of this kind of drugs.

國家自然科學(xué)基金項(xiàng)目（81302796）