注射用益氣復(fù)脈（凍干）源于經(jīng)典古方生脈散，由紅參、麥冬和五味子3味中藥組成，臨床上主要用于治療冠心病勞累型心絞痛及慢性心功能不全等心血管系統(tǒng)疾病。現(xiàn)代藥理研究表明注射用益氣復(fù)脈（凍干）具有增強(qiáng)心臟收縮功能、延緩心室重構(gòu)、改善能量代謝、改善微循環(huán)障礙以及抗氧化等藥理作用。就近10年注射用益氣復(fù)脈（凍干）的藥理作用、臨床應(yīng)用以及不良反應(yīng)發(fā)生情況等內(nèi)容進(jìn)行綜述，為臨床上更加安全合理用藥提供依據(jù)和參考。

Yiqi Fumai Lyophilized Injection (YQFM) is a modern preparation derived from the famous ancient prescription of Sheng-mai San, consisting of three traditional Chinese herbal medicines of Panax ginseng, Ophiopogon japonicus and Schisandra chinensis, mainly used in the clinical treatment of angina pectoris of coronary heart disease, chronic heart failure and other cardiovascular diseases. Modern pharmacological research shows that YQFM has the pharmacological effects of enhancing cardiac contractility, delaying ventricular remodeling, resisting myocardial ischemia/anoxia, improving microcirculation disturbance and anti-oxidation. Pharmacological effects, clinical application and adverse reactions of YQFM in recent 10 years were reviewed in this article, so as to provide evidence and reference for safer and rational drug use in clinic.

天津市中藥注射劑關(guān)鍵技術(shù)校企協(xié)同創(chuàng)新實(shí)驗(yàn)室建設(shè)（17PTSYJC00090）