目的 分析活血解毒丸聯(lián)合阿莫西林分散片對急性乳腺炎患者淋巴細胞、炎癥因子水平及療效影響。方法 回顧性選取2014年1月—2017年2月河南中醫(yī)藥大學(xué)第一附屬醫(yī)院收治的急性乳腺炎患者298例，根據(jù)治療方法不同分為對照組和觀察組。對照組患者采用阿莫西林分散片治療，觀察組患者采用活血解毒丸聯(lián)合阿莫西林分散片治療。觀察兩組患者治療后主要癥狀積分情況、癥狀消失時間、復(fù)發(fā)情況及淋巴細胞、炎癥因子水平變化情況。結(jié)果 兩組患者治療后乳房脹痛、局部皮膚灼熱、乳房結(jié)塊及惡寒發(fā)熱等主要癥狀積分均較治療前改善，同組治療前后比較差異有統(tǒng)計學(xué)意義（P<0.05）；觀察組患者治療后主要癥狀積分均優(yōu)于對照組，差異有統(tǒng)計學(xué)意義（P<0.05）。觀察組患者退熱時間、紅腫消退時間、腫痛消失時間及通乳時間均較對照組短，差異有統(tǒng)計學(xué)意義（P<0.05）。兩組患者治療后淋巴細胞、CRP及IL-6水平均較治療前下降，同組治療前后比較差異有統(tǒng)計學(xué)意義（P<0.05）；觀察組患者治療后淋巴細胞、CRP及IL-6水平均低于對照組，差異有統(tǒng)計學(xué)意義（P<0.05）。觀察組患者1年內(nèi)乳房腫塊、乳房疼痛及乳房溢液的總復(fù)發(fā)率低于對照組，差異有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論 活血解毒丸聯(lián)合阿莫西林分散片治療急性乳腺炎可快速改善患者癥狀，降低患者淋巴細胞、CRP、IL-6水平并減少復(fù)發(fā)。

Objective To analyze the influence of Huoxue Jiedu Pill on lymphocyte, inflammatory factor level and curative effect in patients with acute mastitis. Methods Review from January 2014 to February 2017 in our hospital 298 cases of acute mastitis patients, according to the different treatment methods were divided into control group and observation group. The control group was treated with Amoxicillin Dispersible Tablets treatment, the observation group were treated by Huoxue Jiedu pill combined with Amoxicillin Dispersible Tablets treatment. To observe the main symptoms of the two groups of patients after treatment points, symptoms disappeared time, recurrence and the changes of lymphocytes and inflammatory cytokines. Results Two groups of patients after treatment of breast pain, skin burning, the main symptoms of breast lump and fever and other points were improved compared with before treatment, observation group patients after symptom scores were better than the control group (P<0.05). The patients in the observation group were pyretolysis time, swelling time, swelling and pain disappeared time and Tongru time was shorter than the control group (P<0.05). Two groups of patients after treatment of lymphocytes, CRP and IL-6 levels were lower than that before treatment, patients in the observation group after treatment, CRP lymphocytes, and IL-6 were lower than the control group (P<0.05). The patients in the observation group were within 1 years of breast lumps, breast pain And the total recurrence rate of breast discharge was higher than that of the control group (P<0.05). Conclusion Treatment of acute mastitis with Huoxue Jiedu pills can quickly improve the symptoms of patients, reduce the levels of lymphocytes, CRP, IL-6, and reduce the recurrence rate.