目的 研究阿羅洛爾聯(lián)合依那普利對充血性心力衰竭的臨床治療效果。方法 選擇2012年1月—2016年12月在寶雞市人民醫(yī)院進(jìn)行診治的106例充血性心力衰竭患者，隨機(jī)分為兩組，每組53例。對照組口服依那普利治療，每次5 mg，每天2次，觀察組聯(lián)合口服阿羅洛爾治療，每次5 mg，每天2次。兩組均治療2個月。比較兩組治療前后的N端腦鈉肽前體水平以及左心室射血分?jǐn)?shù)、左心室后壁厚度、左心室舒張末期內(nèi)徑等心功能。結(jié)果 觀察組的有效率為92.45%（49/53），明顯高于對照組的77.36%（41/53），差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組左心室射血分?jǐn)?shù)明顯升高，左心室舒張末期內(nèi)徑和左心室后壁厚度均明顯降低，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且觀察組左心室射血分?jǐn)?shù)明顯高于對照組，左心室舒張末期內(nèi)徑和左心室后壁厚度均明顯低于對照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后兩組的N端腦鈉肽前體水平均明顯降低，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且觀察組明顯低于對照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。兩組的不良反應(yīng)發(fā)生率相比無明顯差異。結(jié)論 阿羅洛爾聯(lián)合依那普利對充血性心力衰竭的臨床治療效果較為顯著，可以有效改善患者的心功能，降低N端腦鈉肽前體水平，安全有效，值得臨床借鑒。

Objective To investigate the clinical effect of aronixil combined with enalapril in the treatment of congestive heart failure. Methods Selected 106 cases of patients with congestive heart failure who were treated in our hospital from January 2012 to December 2016, divided into two groups randomly. The control group was treated with enalapril, 5 times a day, 2 times a day. The observation group was treated with aronixil, 5 times a day, 2 times a day. The clinical effects of two groups were compared. The left ventricular ejection fraction, left ventricular end diastolic diameter, left ventricular posterior wall thickness, cardiac function and the level of N end brain natriuretic peptide were measured before and after treatment. Results After treatment, the effective rate of the observation group was 92.45% (49/53), significantly higher than that of the control group 77.36% (41/53) (P<0.05); the left ventricular ejection fraction, left ventricular end diastolic diameter and left posterior wall thickness of the two groups were significantly improved (P<0.05), and the observation group was significantly better than that of the control group (P<0.05). After treatment, the levels of N end brain natriuretic peptide in the two groups were significantly lower (P<0.05), and the observation group was significantly lower than that of the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups. Conclusion The clinical curative effect of arotinolol combined with enalapril on congestive heart failure is significant, can effectively improve the heart function of patients, reduce the N terminal pro brain natriuretic peptide level, safe and effective, worthy of clinical reference.