[關(guān)鍵詞]
[摘要]
雷公藤屬植物化學(xué)成分復(fù)雜,具有廣泛的藥理作用。現(xiàn)在已經(jīng)從雷公藤屬醋酸乙酯提取部位分離得到多種化學(xué)成分,主要為二萜類、三萜類、倍半萜類、生物堿類及其他化合物;藥理研究表明其具有抗炎、免疫抑制、抗血小板聚集作用和殺蟲活性。對雷公藤屬醋酸乙酯部位化學(xué)成分及藥理作用研究進展進行綜述,為后續(xù)研究提供理論依據(jù)。
[Key word]
[Abstract]
The chemical constituents of Tripterygium are complex and have a wide range of pharmacologic effects. A variety of chemical constituents have been isolated from the ethyl acetate extract of Tripterygium. There are mainly diterpenes, triterpenes, sesquiterpenoids, alkaloids and other compounds. Pharmacological studies have shown that it has anti-inflammatory, immunosuppressive, anti-platelet aggregation and insecticidal activity. This review summarizes the research progress of the chemical constituents and pharmacologic effects of ethyl acetate of Tripterygium, and provides a theoretical basis for the future research.
[中圖分類號]
[基金項目]
福建省自然科學(xué)基金項目(2017J01141,2017J01142);福建省省屬公益類科研院所基本科研專項(2015R1031-1);福建省醫(yī)學(xué)創(chuàng)新科研項目(2017-CX-12);福建省中醫(yī)藥科研項目(2017FJZYZY101)