藥物的吸收、分布、代謝和排泄過程決定了藥物分子在體內的過程和命運。作為常規(guī)生物樣本檢測技術的有效補充，放射性同位素標記示蹤技術如今也被廣泛應用于藥物發(fā)現(xiàn)和開發(fā)過程中的各個階段。特別是其高靈敏性、適用范圍廣的特點使其具有不可比擬的優(yōu)勢。通過對近年來放射性標記技術在藥物評價領域中的應用進行了歸納和梳理，為藥物研發(fā)相關領域研究人員提供可借鑒的參考。

The in vivo process and fate of drug molecules are determined by its absorption, tissue distribution, metabolism and excretion. As an effective complementary to conventional biological sample measurements. Radiolabeled isotope tracing technology has been widespread applied in all stages of drug discovery and development. Due to its high sensitivity and applicability, the radiolabeled approach exhibits advantages. In the review, the application of radiolabeled tracing technology has been reviewed and summarized, which may provide valuable information for scientists in this field.