目的 探討參芪扶正注射液對(duì)乳腺癌TC方案化療患者骨髓抑制及免疫功能的影響。方法 選取2011年l月-2016年12月開封市中醫(yī)院收治的乳腺癌患者92例，將所有患者隨機(jī)分為兩組，分別為對(duì)照組（46例）、觀察組（46例）。對(duì)照組采用TC方案化療，觀察組采用TC化療方案加參芪扶正注射液。所有患者每21天為1個(gè)周期，均化療4周期?；?周期后，評(píng)價(jià)兩組患者的骨髓造血功能和免疫功能。結(jié)果 在骨髓抑制方面，與化療前相比，化療后兩組患者均出現(xiàn)白細(xì)胞明顯減少（P<0.05）；化療后，觀察組白細(xì)胞下降的發(fā)生率低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；化療后，觀察組組血紅蛋白及白細(xì)胞平均恢復(fù)天數(shù)均明顯少于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。在免疫功能方面，化療后，對(duì)照組NK、CD3⁺、CD4⁺、CD8⁺細(xì)胞均較治療前降低，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；觀察組NK、CD3⁺、CD4⁺、CD4⁺/CD8⁺均較化療前升高，差異均具有統(tǒng)計(jì)學(xué)意義（P<0.05），CD8⁺升高不明顯；化療后觀察組NK、CD3⁺、CD4⁺、CD8⁺、CD4⁺/CD8⁺均高于對(duì)照組，差異均具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 參芪扶正注射液可減輕TC方案化療引起的骨髓抑制，增強(qiáng)患者的免疫功能。

Objective To investigate the clinical effects of the Shenqi Fuzheng injection on bone marrow suppression and immune function after TC scheme in treatment of patients with breast cancer. Methods 92 patients with breast cancer in our hospital was choose from January 2011 to December 2016. 92 patients were randomly divided into two groups:the control group (46cases) and the observation group (46 cases).The patients in the control group were administered with TC regimen. The patients in the observation group were treated with TC regimen plus Shenqifuzheng injection. The cycle of chemotherapy was 21d,and total four cycles were performed for all patients. Bone marrow suppression and immune function were evaluated after 4 cycles of chemotherapy in two groups. Results In the bone marrow suppression, white blood cell after chemotherapy was significantly decreased in all patients compared with before chemotherapy (P<0.05), the differences were statistically significant; the incidence of leukocytopenia in the observation group was lower than the control group after chemotherapy (P<0.05), the differences were statistically significant; and average time of recovery in the observation group was shorter than the control group for the hemoglobin and white blood cell, the differences were statistically significant (P<0.05). In immune function in the observation group, NK, CD3⁺,CD4⁺, CD4⁺/CD8⁺ were higher compared with before chemotherapy, the differences were statistically significant (P<0.05), CD8⁺ was increased, but not obviously. After chemotherapy, the NK cell, CD3⁺, CD4⁺, CD8⁺, CD4⁺/CD8⁺ in the observation group were all higher than those in the control group, the differences were statistically significant (P<0.05). Conclusions The Shenqi Fuzheng injection could reduce bone marrow suppression after TC scheme in treatment of patients with breast cancer, and enhance cellular immune function.