隨著我國人口老齡化進(jìn)程加速及居民生活方式的轉(zhuǎn)變，冠心病的發(fā)病率逐年升高。其中，ST段抬高型心肌梗死（STEMI）是冠心病的嚴(yán)重類型，嚴(yán)重危害人們的生命健康。直接經(jīng)皮冠狀動脈介入治療（PPCI）是急性心肌梗死患者的首選治療方式，在國內(nèi)外已廣泛應(yīng)用。然而，盡管該療法可有效地開通心外膜大血管恢復(fù)血供，但仍有部分患者因發(fā)生冠狀動脈微循環(huán)功能障礙導(dǎo)致遠(yuǎn)期不良心血管事件的發(fā)生。因此預(yù)防和治療冠狀動脈微循環(huán)功能障礙是診治急性心肌梗死不可回避且亟待解決的關(guān)鍵科學(xué)問題，具有重要的臨床應(yīng)用價值?，F(xiàn)就冠狀動脈微循環(huán)障礙對急性STEMI的影響及其治療學(xué)研究進(jìn)展做一綜述，為STEMI中冠狀動脈微循環(huán)障礙的診療新策略提供理論依據(jù)和有益的思路。

With the acceleration of population aging and the change of the lifestyle of the residents, the incidence of coronary heart disease is rising gradually. ST-segment elevation myocardial infarction is a serious type of coronary heart disease, which seriously endangers people's life. Primary percutaneous coronary intervention is the first choice for acute myocardial infarction and has been effectively opened. The epicardial large vessel, but there are still some patients with coronary microcirculation dysfunction leading to long-term adverse cardiovascular events. Therefore, the prevention and treatment of coronary microcirculation dysfunction is an unavoidable problem in the diagnosis and treatment of acute myocardial infarction. The acute ST-segment of the coronary artery microcirculation disorder is now on the acute segment of the coronary artery. The effect and treatment of elevation myocardial infarction were reviewed to provide evidence for the diagnosis and treatment of coronary microcirculation obstrcation.

江蘇大學(xué)臨床醫(yī)學(xué)科技發(fā)展基金（編號JLY20140059）