目的 研究注射用丹參多酚酸對急性腦梗死患者血液流變學、凝血功能以及血清氧化低密度脂蛋白（ox-LDL）、降鈣素原（PCT）、單核細胞趨化蛋白-1（MCP-1）、胰島素樣生長因子-1（IGF-1）水平的影響。方法 選取河南大學淮河醫(yī)院診治的94例急性腦梗死患者，隨機分為對照組和觀察組，每組47例。入院后所有患者均根據(jù)自身情況給予綜合治療，而觀察組在此基礎上加用注射用丹參多酚酸。治療前和治療14 d后對兩組患者的血液流變學、凝血功能以及血清ox-LDL、PCT、MCP-1、IGF-1水平進行檢測和比較。結(jié)果 治療前，兩組患者的各項指標之間均不存在統(tǒng)計學差異。治療后，兩組患者的血液流變學相關(guān)指標全血黏度（WBV）、血漿黏度（PV）、紅細胞聚集指數(shù)（EAI）、紅細胞變形指數(shù)（EDI）、紅細胞比容（Hct）水平和凝血功能相關(guān)指標血小板計數(shù)（PLT）、纖維蛋白原（Fib）、D-二聚體（D-D）水平以及血清ox-LDL、PCT、MCP-1水平均顯著降低，IGF-1水平顯著升高，與同組治療前存在統(tǒng)計學差異（P<0.05），兩組之間水平也均存在統(tǒng)計學差異（P<0.05）。結(jié)論 對急性腦梗死患者在綜合內(nèi)科治療的基礎上加用注射用丹參多酚酸，不僅可以更加明顯地改善患者的血液流變學和凝血功能，而且能夠降低患者血清ox-LDL、PCT、MCP-1水平，提高IGF-1水平，值得臨床上進一步研究。

Objective To study the influence of Salvianolic Acids for Injection on hemorheology, coagulation function and serum levels of ox-LDL, PCT, MCP-1 and IGF-1 in patients with acute cerebral infarction. Methods To choose 94 cases of acute cerebral infarction in our hospital, randomly divided into the control group and observation group, 47 cases in each group. All patients were given comprehensive treatment according to their own condition after admission, and the observation group were added Salvianolic Acids for Injection on the basis. Before and after 14 days of treatment, detected and compare the hemorheology, coagulation function and serum levels of ox-LDL, PCT, MCP-1 and IGF-1 in the two groups. Results Before treatment, there was no statistical difference in various indicators between the two groups. After treatment, the hemorheology ralated indexes in the levels of WBV, PV, EAI, EDI, Hct and the coagulation function related indexes in the levels of PLT, Fib, D-D and the serum levels of ox-LDL, PCT, MCP-1 in the two groups were significantly decreased, the levels of IGF-1 significantly increased, there was a statistical difference compared with the same group before treatment (P<0.05), and the difference between the two groups had statistical significance (P<0.05). Conclusion Salvianolic Acids for Injection was added to the patients with acute cerebral infarction on the basis of comprehensive medical treatment, it could improve the hemorheology and coagulation function of patients more obviously, and reduce the serum levels of ox-LDL, PCT, MCP-1, increase IGF-1 level, it was worthy for further clinical study.