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[摘要]
目的 研究注射用丹參多酚酸治療急性腦梗死的臨床療效。方法 隨機(jī)抽取吉林省神經(jīng)精神病醫(yī)院2017年3月-2018年7月入院的60例急性腦梗死患者為研究對象,按住院先后順序編號(hào),以隨機(jī)選取分組法分為對照組與觀察組,每組各30例。對照組采取常規(guī)抗血小板聚集、改善微循環(huán)等治療方案,觀察組在此基礎(chǔ)上加用注射用丹參多酚酸治療,兩組療程均為2周,比較治療前后2組美國國立衛(wèi)生研究院卒中量表(NIHSS)評分、日常生活能力(ADL)評分及蒙特利爾認(rèn)知評估量表(MoCA)評分,評估治療效果,統(tǒng)計(jì)不良反應(yīng)。結(jié)果 治療2周后,對照組總有效率為66.7%,觀察組總有效率為80.0%,經(jīng)對比差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后兩組NIHSS評分明顯降低,ADL評分及MoCA評分均明顯升高,同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05);且治療后觀察組NIHSS評分明顯低于對照組,ADL評分及MoCA評分均明顯高于對照組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療期間2組均未見不良反應(yīng)發(fā)生。結(jié)論 注射用丹參多酚酸對急性腦梗死的治療安全、有效,在臨床中值得推廣。
[Key word]
[Abstract]
Objective To study the clinical efficacy of Salvianolic Acids for Injection in treatment of acute cerebral infarction. Method Randomly draw our hospital Sixty patients with acute cerebral infarction who were admitted between 2017-03 and 2018-07 were enrolled in the study. They were numbered according to the order of hospitalization. They were randomly divided into control group and treatment group, with 30 cases in each group. The control group received conventional anti-platelet aggregation and microcirculation to improve the treatment. The treatment group was treated with injection of Salvianolic Acids for Injection. The two groups were treated for 2 weeks. The NIHSS scores of the two groups before and after treatment were compared to evaluate the therapeutic effect. Medical statistics adverse reaction comparison. Results After 2 weeks of treatment, the total effective rate of the control group was 66.7%, and the total effective rate of the treatment group was 80.0%. The difference was statistically significant (P<0.05). After treatment, the NIHSS score of the treatment group decreased to (4.1 ±2.1). There was a difference between the control group and the control group, and the difference was statistically significant (P<0.05). After treatment, the ADL score of the treatment group increased to (73.7 ±10.3) points, which was different from the control group, and the difference was Statistical significance (P<0.05); after treatment, the MoCA score of the treatment group increased to (18.7±4.2) points, compared with the control group, and the difference was statistically significant (P<0.05). No adverse reactions occurred. Conclusion Salvianolic Acids for Injection is safe and effective in the treatment of acute cerebral infarction, and it is worthy of promotion in clinical practice.
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