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[摘要]
目的 研究注射用丹參多酚酸對急性缺血性腦卒中的臨床療效。方法 選取急性缺血性腦卒中患者200例,隨機分為觀察組和對照組,各100例。納入研究的200例患者均給予常規(guī)抗凝[阿司匹林(100~300)mg/d]、降脂(阿托伐他汀20 mg/d)及非丹參類中成藥進行治療,觀察組在此基礎(chǔ)上再給予注射用丹參多酚酸100 mg/d靜脈滴注。兩組均以14 d為1個療程,評價患者的臨床療效、神經(jīng)功能缺損情況(NIHSS評分)、日常生活能力(ADL評分)。結(jié)果 觀察組總有效率為91%,顯著高于對照組的75%(P<0.05)。兩組治療前后比較,NIHSS評分明顯降低,ADL評分明顯升高,差異具有統(tǒng)計學(xué)意義(P<0.05);治療后觀察組的NIHSS評分和ADL評分改善程度顯著優(yōu)于對照組(P<0.05)。結(jié)論 注射用丹參多酚酸對急性缺血性腦卒中神經(jīng)功能的恢復(fù)有一定的促進作用。
[Key word]
[Abstract]
Objective To study the clinical effect of Salvianolic Acids for Injection on acute ischemic stroke. Methods Tatolly 200 patients with acute ischemic stroke were randomly divided into observation and control group. The patients in control group were treated with routine medical treatment, while those in observation group were treated with Salvianolic Acids for Injection on the basis of routine treatment. The clinical curative effect, neurological deficit (NIHSS score) and activities of daily living (ADL) of the patients in both groups were observed after 14 days as a course of treatment. Results The total effective rate of observation group was 91%, and the total effective rate was significantly higher than that in the control group (75%) (P<0.05). After treatment, the improvement of neurological deficit and Barthel index in observation group were significantly better than that in control group (P<0 05). Conclusion Salvianolic Acids for Injection can promote the recovery of neurological function in acute ischemic stroke.
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