[關(guān)鍵詞]
[摘要]
目的 觀察注射用丹參多酚酸聯(lián)合疏血通治療腦梗死的臨床療效。方法 將68例急性腦梗死患者隨機分為兩組,各34例。對照組用疏血通6 mL加0.9%氯化鈉250 mL,靜脈滴注,1次/d;觀察組在對照組基礎(chǔ)上加用注射用丹參多酚酸0.13 g加0.9%氯化鈉250 mL,靜脈滴注,1次/d,兩組均治療14 d,比較兩組的臨床有效率以及血液流變學(xué)指標(biāo)。結(jié)果 治療后,觀察組臨床總有效率79.41%,高于對照組的55.88%,觀察組的臨床療效優(yōu)于對照組的(P<0.05);兩組血液黏度、血漿黏度和血漿纖維蛋白原較治療前均有改善(P<0.05),且觀察組改善程度較對照組更為顯著(P<0.05)。結(jié)論 注射用丹參多酚酸聯(lián)合疏血通治療腦梗死能有效控制病情發(fā)展,療效顯著,值得臨床推廣。
[Key word]
[Abstract]
Objective To observe the effect of Salvianolic Acids for Injection (SAFI) combined with Shuxuetong Injection in treatment of cerebral infarction. Methods A total of 68 patients with cerebral infarction were randomly divided into observation group (n=34) and control group (n=34). The control group were treated with Shuxuetong Injection 6 mL added into 0.9% normal saline 250 mL, intravenous drip once daily. The observation group were treated with Shuxuetong Injection combined with SAFI 0.13 g added for 0.9% sodium chloride 250 mL, intravenous drip once daily. All patients in the two groups were treated for 14 d, and the clinical effective rate and hemorheological indexesof two groups were compared. Results After treatment, the total effective rate of the observation group 79.41% was significantly higher than that of the control group 55.88% (P<0.05). The clinical effect of the observation group was better than that of the control group (P<0.05). The blood viscosity, plasma viscosity, and plasma fibrinogen (FIB) of the observation group were significantly lower than those of the control group (P<0.05). Conclusion Salvianolic Acids for Injection combined with Shuxuetong Injection have significant clinical effect on the progression of cerebral infarction, and the curative effect is remarkable and worthy of clinical promotion.
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