目的 觀察注射用丹參多酚酸治療急性腦梗死的臨床療效。方法 選擇發(fā)病時(shí)間在72 h內(nèi)的急性腦梗死住院患者100例，隨機(jī)分為觀察組和對(duì)照組，每組50例。對(duì)照組給予抗血小板聚集、清除自由基等常規(guī)治療，觀察組在對(duì)照組治療基礎(chǔ)上給予注射用丹參多酚酸130 mg，溶于0.9%氯化鈉注射液250 mL中靜脈滴注，1次/d，兩組均治療14 d。治療前后分別采用歐洲卒中分量表神經(jīng)功能評(píng)分（ESS）和日常生活能力評(píng)分（Barthel ADL指數(shù)）進(jìn)行判定，對(duì)兩組的臨床療效進(jìn)行比較。結(jié)果 治療2周后，觀察組總有效率90.0%，高于對(duì)照組的76.0%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；觀察組與對(duì)照組的ESS評(píng)分和Barthel ADL指數(shù)較治療前均有改善，差異有統(tǒng)計(jì)學(xué)意義（P<0.05），且觀察組的優(yōu)于對(duì)照組的（P<0.05）。結(jié)論 注射用丹參多酚酸對(duì)改善急性腦梗死患者的行為障礙和神經(jīng)癥狀有較好的療效。

Objective To observe the clinical effect of Salvianolic Acids for Injection (SAFI) in treatment of acute cerebral infarction. Methods A total of 100 patients with acute cerebral infarction and the onset time within 72 h, were randomly divided into the treatment group and the control group, 50 cases in each group.The control group was given routine treatment such as antiplatelet aggregation and free radical scavenging. The observation group was given 130 mg SAFI dissolved in 0.9% sodium chloride injection 250 mL by intravenous drip once a day based on the treatment of the control group. Patients in the both groups were treated for 14 d. Before and after treatment with the European stroke subscales neurologic evaluation (ESS) score and daily activity score (Barthel ADL index) were used to determine the clinical efficacy of the two groups. Results After two weeks of treatment, the total effective rate was 90.0% in the treatment group and 76.0% in the control group. The difference between the two groups was statistically significant (P<0.05). The improvement of ESS score and Barthel ADL index in two groups were better than those before treatment (P<0.05), and treatment groups were better than those in control groups (P<0.05). Conclusion SAFI has a good effect on improving behavioral disorder and neurological symptoms in patients with acute cerebral infarction.