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[摘要]
目的 觀察和分析注射用丹參多酚酸治療血管源性眩暈的效果和安全性。方法 選取許昌市中心醫(yī)院神經(jīng)內(nèi)科2017年10月-2018年6月住院的血管源性眩暈病例100例,按照治療方法的不同分為常規(guī)治療組、丹參多酚酸治療組、丁苯酞治療組,治療前后分別應(yīng)用眩暈障礙量表(DHI)進(jìn)行眩暈程度評定,觀察3組患者治療后結(jié)果的差別,并監(jiān)測治療期間的藥物不良反應(yīng)。結(jié)果 3組患者治療后的DHI評分均低于治療前,差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。丹參多酚酸組DHI改善情況優(yōu)于常規(guī)組,差異具有統(tǒng)計(jì)學(xué)意義(P<0.05);丁苯酞治療組DHI改善情況優(yōu)于常規(guī)組,差異具有統(tǒng)計(jì)學(xué)意義(P<0.05);丹參多酚酸組和丁苯酞組DHI改善情況不具有統(tǒng)計(jì)學(xué)意義。丹參多酚酸組患者治療期間不良反應(yīng)發(fā)生率最低。結(jié)論 注射用丹參多酚酸在治療眩暈方面具有明顯效果,無明顯不良反應(yīng)。
[Key word]
[Abstract]
Objects To observe and analyze the efficacy and safety of Salvianolic Acids for Injection in treatment of vasogenic vertigo. Methods 100 cases of vasogenic vertigo patients in the Department of Neurology Xuchang Central Hospital from October 2017 to June 2018, According to the different treatment methods, all patients were divided into the conventional treatment group, the Salvianolic Acids for Injection treatment group, and the butylphthalide treatment group. Assessment of vertigo using the dizziness handicap inventory(DHI) before and after treatment. The differences in outcomes between the three groups of patients were observed and the adverse drug reactions during the treatment were monitored. Results The DHI scores of the three groups after treatment were lower than before treatment, and the difference was statistically significant (P<0.05). The improvement of DHI in Salvianolate Injection group was better than that in the conventional group, and the difference was statistically significant (P<0.05). The improvement of DHI in the butylphthalide treatment group was better than that in the conventional group, and the difference was statistically significant (P<0.05). The improvement of DHI in the Salvianolic Acids for Injection group and the butylphthalide group was not statistically significant. No significant adverse reactions occurred during the treatment of the three groups of patients. Conclusions Salvianolic Acids for Injection has obvious effects in treating vertigo, and no obvious adverse reactions.
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