注射用丹參多酚酸是以丹參的水溶性有效部位丹參多酚酸為活性成分制成的凍干粉針劑，主要化學成分為丹酚酸B、迷迭香酸、紫草酸、丹酚酸D及丹酚酸Y等水溶性酚酸類成分。臨床上用于中風病中經(jīng)絡（輕中度腦梗死）恢復期瘀血阻絡證，治療輕中度腦梗死引起的半身不遂、口舌歪斜、舌強言蹇、偏身麻木的癥狀。就近10年注射用丹參多酚酸的化學成分、藥材質量評價、產品質量控制方法、配伍合理性及藥動學研究進展進行綜述，為臨床上更加安全合理使用該藥提供依據(jù)和參考。

Salvianolic Acids for Injection (SAFI) is a traditional Chinese medicinal preparation composed of multiple salvianolic acids from the aqueous extracts of Salvia miltiorrhiza. The main chemical components include salvianolic acid B, rosmarinic acid, lithospermic acid, salvianolic acid D, salvianolic acid Y and other aqueous phenolic acids. SAFI is mainly used for the treatment of stroke. In this article, the contents of chemical components, quality control of raw materials and preparation, compatibility, and pharmacokinetics in the past 10 years are reviewed, providing a basis and reference for safer and rational drug use in clinic.

天津市中藥注射劑關鍵技術校企協(xié)同創(chuàng)新實驗室建設（項目編號：17PTSYJC00090）