目的 探討馬來酸麥角新堿注射液在疤痕子宮孕產(chǎn)婦術(shù)后子宮復(fù)舊的有效性。方法 以60例具有剖宮產(chǎn)指征的疤痕子宮患者為研究對(duì)象。將患者隨機(jī)分成觀察組和對(duì)照組，產(chǎn)后分別給予馬來酸麥角新堿和縮宮素治療3 d。觀察兩組術(shù)后子宮大小變化、出血量、宮腔積液情況及惡露消失時(shí)間。結(jié)果 術(shù)后3、42 d觀察組子宮大小三徑之和分別為（29.9±2.0）cm、（15.8±±1.2）cm，顯著低于對(duì)照組的（32.6±2.8）cm、（18.1±1.5）cm（P<0.05）；觀察組術(shù)后24、48 h出血量、42 d宮腔積液發(fā)生率、產(chǎn)后惡露消失時(shí)間均顯著少于對(duì)照組（P<0.05）。結(jié)論 馬來酸麥角新堿可有效修復(fù)剖宮產(chǎn)后子宮，減少術(shù)后出血量、產(chǎn)后宮腔積液發(fā)生率及縮短惡露消失時(shí)間，提高子宮復(fù)舊效率。

Objective To evaluate the efficacy of Ergometrine Maleate Injection in accelerating postpartum uterine involution for women with scarred uterus. Methods The study included 60 cases of parturient women, who had indications for cesarean delivery, and with previously scarred uterus. The patients were randomized to receive either ergometrine in treatment group or oxytocin in control group, for 3 days following delivery. Uterine size after operation, amount of postoperative hemorrhage, incidence of hydrometra, and duration of lochia were compared between the two groups. Results The sum of uterine longitudinal, anteroposterior and transverse diameter on the 3rd and 42nd day were (29.9 ±2.0) cm and (15.8 ±1.2) cm respectively, less than those in control group (32.6 ±2.8) cm and (18.1 ±1.5) cm, P<0.05). Blood loss within 24 and 48 hours after operation, incidence of hydrometra on the 42nd day, and duration of lochia in treatment group were less than those in control group (P<0.05). Conclusion Ergometrine maleate significantly reduces volume of post-cesarean uterus, diminishes postpartum blood loss, decreases incidence of hydrometra, shortens duration of lochia, and thus hastens uterine involution.

R969.4