目的 分析西充縣人民醫(yī)院2012-2017年藥品不良反應（ADR）發(fā)生的規(guī)律和特點，為進一步加強該院ADR監(jiān)測水平和臨床安全用藥提供參考。方法 對西充縣人民醫(yī)院2012-2017年ADR報告進行整理匯總，對患者性別組成、年齡分布、給藥途徑，ADR類型以及藥品種類等進行統(tǒng)計分析。結(jié)果 2012-2017年ADR報告例數(shù)逐年上升，共納入843例ADR報告進行分析，其中男性占50.42%，女性占49.58%；老年患者ADR發(fā)生率占比最高；抗感染藥物類、消化系統(tǒng)類藥物、心血管系統(tǒng)類藥物以及電解質(zhì)和營養(yǎng)藥ADR發(fā)生率較高，但抗感染藥物ADR發(fā)生風險呈現(xiàn)逐年下降的趨勢。結(jié)論 近6年來西充縣人民醫(yī)院ADR報告質(zhì)量逐年提升，但仍需持續(xù)提高藥品管理水平，規(guī)范醫(yī)療用藥的合理性和安全性，減少患者用藥的不適感和安全風險，以期促進該院不良反應監(jiān)測工作上升到一個新臺階。

Objective To analyze the regularity and characteristics of the adverse drug reaction (ADR) in Xichong County People's Hospital from 2012 to 2017, and provide reference for further strengthening the ADR monitoring level and clinical safety medication in our hospital. Methods The ADR reports of this hospital from 2012 to 2017 was compiled and summarized, and the patient's gender composition, age distribution, administration route, ADR type and drug type were statistically analyzed. Results The number of ADR reports in 2012-2017 increased year by year. A total of 843 ADR reports were included for analysis. Among them, 50.42% were men and 49.58% were women. The incidence of ADR was the highest in elderly patients. The ADR incidence of anti-infective drugs, digestive system drugs, cardiovascular system drugs and electrolytes and nutrients ADR was higher, but the risk of antiinfective drugs ADR was in a decreasing trend year by year. Conclusion In the past six years, the quality of ADR reports in Xichong County People's Hospital has increased by yeard, but it is still necessary to continuously improve the level of drug management, standardize the rationality and safety of medical drugs, reduce the discomfort and safety risks of patients, in order to promote the monitoring of adverse reactions in this hospital to a new step.

R969.3