心力衰竭是威脅人類健康的重大疾病之一，其病理機(jī)制復(fù)雜，中醫(yī)藥防治心衰具有顯著特色。中醫(yī)理論認(rèn)為氣陰兩虛是心衰患者的主要證候之一，生脈散為益氣養(yǎng)陰的代表方。目前根據(jù)生脈散研制的中成藥包括注射用益氣復(fù)脈、生脈注射液、生脈散、生脈飲、參麥注射液、生脈膠囊等，被廣泛用于治療心腦血管疾病。從生脈方改善線粒體功能、抑制心室重塑、減輕心肌細(xì)胞的炎性反應(yīng)3個(gè)方面綜述了生脈方治療心衰的研究進(jìn)展，以期為心衰的防治提供依據(jù)。

Heart failure is one of the major diseases that threaten human health, its pathological mechanism is complex, and the prevention and treatment of heart failure by Traditional Chinese Medicine (TCM) has significant advantages. The theories of TCM believes that deficiency of both Qi and Yin was one of the main syndromes of heart failure patients, and Shengmai San is a representative side of nourishing Qi and nourishing Yin. The current Chinese patent medicines developed based on Shengmai Powder include Yiqi Fumai for Injection, Shengmai Injection, Shengmai Powder, Shengmai Yin, Shenmai Injection, Shengmai Capsules and other products are widely used to treat cardiovascular and cerebrovascular diseases. This article reviews the research progress of Shengmai prescription in treating heart failure from three aspects:improving mitochondrial function, inhibiting ventricular remodeling, and reducing the inflammatory response of myocardial cells, in order to provide some clues and basis for the prevention and treatment of heart failure.

R285.6;R286.2

天津市科技重大專項(xiàng)與工程（18ZXXYSY00120）