目的 了解注射用丹參多酚酸臨床應(yīng)用及不良反應(yīng)發(fā)生情況，為臨床應(yīng)用提供該藥品安全性評價依據(jù)。方法 選取吉林大學(xué)第一醫(yī)院二部2019年1-10月使用注射用丹參多酚酸的住院患者350例，利用醫(yī)院信息管理系統(tǒng)（HIS）采集數(shù)據(jù)，從適應(yīng)癥、療程、給藥劑量、溶媒種類、溶媒體積、給藥頻次、滴速、是否沖管、合并用藥等方面進行統(tǒng)計分析。結(jié)果 350例用藥患者均標注滴注速度，均無藥物不良反應(yīng)發(fā)生。適應(yīng)癥不適宜比例為23.43%，選用溶媒不適宜占2.57%，療程不足占91.71%，超療程用藥占2.29%，換液未沖管占71.43%，合并用藥占25.43%，重復(fù)用藥占2.57%。結(jié)論 注射用丹參多酚酸具有較好的安全性，臨床使用中存在換液未沖管、療程不足、合并用藥等現(xiàn)象，應(yīng)加強用藥安全管理。

Objective To investigate the clinical application and adverse reactions of Salvianolic Acid for Injection, and to provide the safety evaluation of the drug for clinical application. Methods In patients using Salvianolic Acid for Injection were selected by hospital information management system (HIS) from January to October 2019 in the First Hospital of Jilin University-the Eastern Division. The indications, course of treatment, dosage, type and volume of solvent, frequency of administration, drop rate, and combination of drugs were analyzed statistically. Results A total of 350 patients were labeled with infusion speed, and no adverse drug reactions occurred. The proportion of unsuitable indications was 23.43%, the proportion of unsuitable solvent was 2.57%, the proportion of inadequate course of treatment was 91.71%, the proportion of over-course of treatment was 2.29%, the proportion of unflushed tube was 71.43%, the proportion of combined treatment was 25.43%, and the proportion of repeated treatment was 2.57%. Conclusion Salvianolic Acid for Injection has good safety, and there are some problems in clinical application, such as unflushed tube and short course of treatment which should be strengthened.

R969.3