目的 觀察注射用丹參多酚酸治療恢復(fù)期腦干梗死的療效與安全性。方法 收集駐馬店市中心醫(yī)院2017年1月-2019年12月收治的恢復(fù)期腦干梗死住院患者80例，隨機(jī)分為對(duì)照組及觀察組，每組40例。對(duì)照組給予抗血小板聚集、降脂等治療，觀察組在對(duì)照組基礎(chǔ)上加用注射用丹參多酚酸0.13 g+0.9%氯化鈉注射液250 mL，靜脈滴注，1次/d，兩組均治療14 d。比較兩組患者美國(guó)國(guó)立衛(wèi)生研究院卒中量表（NIHSS）評(píng)分、日常生活能力（Bathel指數(shù)）評(píng)分、療效及不良反應(yīng)。結(jié)果 治療前兩組患者的NIHSS評(píng)分、日常生活能力評(píng)分無(wú)統(tǒng)計(jì)學(xué)差異。治療后，兩組NIHSS評(píng)分均低于治療前（P<0.05），且觀察組低于對(duì)照組（P<0.05）；兩組日常生活能力評(píng)分均較治療前提高（P<0.05），且觀察組較對(duì)照組明顯提高（P<0.05）；觀察組總有效率95.00%，明顯高于對(duì)照組的82.50%（P<0.05）。兩組未見(jiàn)明顯的不良反應(yīng)。結(jié)論 注射用丹參多酚酸治療恢復(fù)期腦干梗死效果良好，可提高總有效率，且用藥安全。

Objective To observe the clinical efficacy and safety of Salvianolic Acid for Injection in treatment of convalescent brainstem infarction. Methods A total of 80 convalescent patients with convalescent brainstem infarction in Zhumadian Central Hospital from January 2017 to December 2019 were selected and divided randomly into control group and observation group, 40 patients in each group. The control group was given anti-platelet aggregation, lipid-lowering treatment, etc. The observation group was added to the control group with Salvianolic Acid for Injection 0.13g + 0.9% sodium chloride injection 250 mL, intravenous drip, once per day, both groups were treated for 14 days. The national Institutes of Health Stroke Scale (NIHSS) score, daily life ability (Bathel Index) score, treatment effect and adverse reactions were compared between two groups. Results There were no statistical difference in NIHSS score and Bathel Index between two groups before treatment. After treatment, NIHSS scores in both groups were lower than those before treatment (P<0.05), and NIHSS scores in the observation group were lower than those in the control group, with statistically significant differences (P<0.05). The Bathel Index of both groups was improved compared with that before treatment (P<0.05), and was significantly improved in the observation group compared with the control group (P<0.05). The cure rate of 95.00% in the observation group was significantly higher than 82.50% in the control group (P<0.05). There was no adverse reactions in two groups. Conclusion Salvianolic acid for Injection in the treatment of convalescent brainstem infarction is effective, can improve the cure rate, and it is safety.

R285.6;R286.1