[關(guān)鍵詞]
[摘要]
目的 分析確診為新型冠狀病毒肺炎(COVID-19)患者的中藥飲片治療處方,統(tǒng)計分析用藥規(guī)律。方法 收集湖北省中西醫(yī)結(jié)合醫(yī)院2020年2月1日—2月29日6個呼吸內(nèi)科病區(qū)治療COVID-19的中藥處方,利用Excel、SPSS 25軟件進行頻數(shù)頻率分析、關(guān)聯(lián)分析、聚類分析等。結(jié)果 共納入361例COVID-19患者治療用中藥處方共計529張,中藥處方使用了292味中藥,使用頻數(shù)前5位的中藥為茯苓、甘草、法半夏、陳皮、黃芩;中藥類別頻數(shù)前5位的為補虛藥、化痰止咳平喘藥、清熱藥、解表藥、化濕藥;關(guān)聯(lián)規(guī)則顯示,支持度最高的藥對為茯苓和法半夏,置信度最高的藥對為麩炒白術(shù)和茯苓;聚類分析共得11個聚類方。結(jié)論 通過對所收集COVID-19用藥數(shù)據(jù)進行分析,發(fā)現(xiàn)了中藥以補虛為主,辨證加入化痰、止咳、平喘、清熱、健脾化濕的用藥及組方特點,與國家發(fā)布的COVID-19診療中醫(yī)藥治療用藥基本一致,為COVID-19的中醫(yī)藥治療提供了參考。
[Key word]
[Abstract]
Objective Analyzed the prescriptions of traditional Chinese medicine (TCM) for patients diagnosed with Novel Coronavirus Pneumonia (COVID-19), and the medication patterns were statistically analyzed to provide reference for the treatment of COVID-19. Methods Chinese medicine prescriptions for COVID-19 were collected from six respiratory wards in Hubei Provincial Hospital of Integrated Chinese and Western Medicine hospital from February 1 to February 29, 2020. The Excel and SPSS 25 software were used in the frequency analysis, association analysis, cluster analysis, etc. Results In this study, a total of 361 COVID-19 patients were enrolled with 529 TCM prescriptions, and 292 TCM were used in these prescriptions. The top five Chinese herbs with highest frequency include:Fuling(Poria), Gancao (Glycyrrhizae Radix), Fabanxia (Pinelliae Rhizoma Praeparatum), Chenpi(Citri Reticulatae Pericarpium), Huangqin (Scutellaria Baicalensis). The most frequently used five categories of Chinese herbs include:medicine for tonify deficiency, dissolving phlegm, relieving cough and calming panting, clearing heat, and relieving exterior, clearing damp. The analysis based on association rule showed that Fuling and Fabanxia had the highest support. Fuchao cangzhu and Fuling had the highest confidence. A total of 11 clustering methods were obtained by cluster analysis. Conclusion Through the data analysis of treatment of COVID-19 in our hospital, it shows that the main treatment of COVID-19 in our hospital was tonic deficiency, combined with resolving phlegm, relieving cough, calming panting, clearing heat, clearing damp and invigorating spleen based on syndrome differentiation. These main treatments are basically consistent with the COVID-19 diagnosis and treatment medication of TCM released by the national health commission, which will provides reference for the TCM treatment of COVID-19.
[中圖分類號]
[基金項目]
國家中醫(yī)藥管理局2019年全國中藥特色技術(shù)傳承人才培訓(xùn)項目(國中醫(yī)藥人教函[2019]43號)