目的 探討松齡血脈康膠囊聯(lián)合氟桂利嗪治療慢性腦供血不足的臨床療效。方法 選取2016年9月-2018年9月新疆心腦血管病醫(yī)院158例慢性腦供血不足患者作為研究對(duì)象，根據(jù)隨機(jī)抽簽原則將患者分為對(duì)照組和觀察組，每組各79例。對(duì)照組患者口服鹽酸氟桂利嗪膠囊，1粒/次，1次/d；觀察組患者在對(duì)照組的基礎(chǔ)上口服松齡血脈康膠囊，1.5 g/次，3次/d。兩組患者均連續(xù)治療2個(gè)月。觀察兩組患者的臨床療效，同時(shí)比較兩組治療前后的腦血流速度和血脂水平。結(jié)果 治療后，觀察組患者總有效率為93.67%，對(duì)照組患者總有效率為77.22%，兩組比較存在統(tǒng)計(jì)學(xué)差異（P<0.05）。治療后，兩組患者的各動(dòng)脈血流速度均明顯升高（P<0.05），且觀察組各動(dòng)脈血流速度顯著高于對(duì)照組（P<0.05）。治療后，兩組患者高密度脂蛋白膽固醇（HDL-C）、低密度脂蛋白膽固醇（LDL-C）、三酰甘油（TG）和膽固醇（TC）水平均明顯改善（P<0.05），且觀察組血脂水平顯著優(yōu)于對(duì)照組（P<0.05）。結(jié)論 松齡血脈康膠囊聯(lián)合氟桂利嗪可有效改善患者的腦血流速度及血脂水平，臨床療效顯著，在慢性腦供血不足治療中具有較高的應(yīng)用價(jià)值。

Objective To investigate the clinical effect of Songling Xuemakang Capsules combined with flunarizine in treatment of chronic cerebral insufficiency. Methods A total of 158 patients with chronic cerebral insufficiency in Xinjiang Cardiovascular and Vascular Disease Hospital from September 2016 to September 2018 were selected as the research objects, and the patients were divided into the control group and the observation group according to the principle of random lottery, with 79 patients in each group. Patients in the control group were po administered with Flunarizine Hydrochloride Capsules, 1 capsule/time, once daily. Patients in the observation group were po administered with Songling Xuemakang Capsules on the basis of control group, 1.5 g/time, three times daily. Two groups of patients were treated for 2 months. After treatment, the clinical efficacy in two groups were observed, and the cerebral blood flow velocity and blood lipid level before and after treatment were compared. Results After treatment, the total effective rate was 93.67% in the observation group and 77.22% in the control group, showing statistical difference between the two groups (P<0.05). After treatment, the blood flow velocity of each artery in two groups was significantly increased (P<0.05), and the blood flow velocity of each artery in the observation group was significantly higher than those in the control group (P<0.05). After treatment, the levels of HDL-C, LDL-C, TG and TC in two groups were significantly improved (P<0.05), and the lipid level in the observation group was significantly better than that in the control group (P<0.05). Conclusion Songling Xuemaikang Capsules combined with flunarizine can effectively improve the cerebral blood flow velocity and blood lipid level of patients, with significant clinical efficacy, and has high application value in the treatment of chronic cerebral insufficiency.

R971