Ames試驗是一項體外致突變性試驗，被廣泛用于藥物、食品、化學品和農(nóng)藥的遺傳毒性檢測，以評價受試物致突變的可能性。藥物、食品、化學品和農(nóng)藥的指導原則和國家標準中Ames試驗方法不盡相同，就這幾者Ames試驗方法的主要異同點進行比較分析，以期能熟練掌握Ames試驗實施要點，更加規(guī)范實施檢測工作，不斷提高試驗質(zhì)量。

Ames test is a mutagenicity test in vitro, which is widely used in the detection of genotoxicity of drugs, food, chemicals and pesticides to evaluate the possibility of mutagenicity of test substance. The guiding principles and national standards of Ames test on drugs, food, chemicals and pesticidesand are different. In this paper, the main similarities and differences were compared and analyzed in order to master the key points of Ames test implementation, so we can implement the testing work standardly and improve the test quality constantly.

R962.2

山東省創(chuàng)新公共服務(wù)平臺項目（2015CXPT00001）