目的探討丹參酮Ⅱ_A磺酸鈉注射液聯(lián)合胺碘酮治療室性早搏的療效。方法選取2018年7月-2020年3月阜陽市腫瘤醫(yī)院收治的96例室性早搏患者作為研究對象，按照治療方法將患者分為對照組和觀察組，每組各48例。對照組患者口服鹽酸胺碘酮片，0.2 g/次，3次/d。觀察組在對照組的基礎(chǔ)上靜脈滴注丹參酮Ⅱ_A磺酸鈉注射液，80 mg/次，1次/d。兩組均連續(xù)治療2周。觀察兩組患者的臨床療效，同時比較兩組治療前后的室性早搏次數(shù)、ST段下移時間、ST段壓低距離、每搏輸出量（SV）、心輸出量（CO）、阻力指數(shù)（RI）。結(jié)果治療后，觀察組臨床總有效率93.75%，顯著高于對照組的79.17%，差異有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組的室性早搏次數(shù)、ST段下移時間、ST段壓低距離均顯著降低（P<0.05）；觀察組治療后的室性早搏次數(shù)、ST段下移時間、ST段壓低距離均低于對照組，差異有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組的SV、CO顯著升高，RI顯著降低（P<0.05）；觀察組治療后的SV、CO高于對照組，RI低于對照組，差異有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論丹參酮Ⅱ_A磺酸鈉注射液聯(lián)合胺碘酮可提高室性早搏的療效，改善患者血流動力學(xué)，改善心電圖的水平，安全性較好，具有良好的臨床研究價值。

Objective To investigate the effect of Sulfotanshinone Sodium Injection combined with amiodarone in treatment of patients with ventricular premature beats. Methods A total of 96 patients with ventricular premature beats admitted to Fuyang Cancer Hospital from July 2018 to March 2020 were selected as the research subjects. According to the treatment methods, the patients were divided into control group and observation group, with 48 patients in each group. Patients in the control group were po administered with Amiodarone Hydrochloride Tablets, 0.2 g/time, three times daily. Patients in the observation group were iv administered with Sulfotanshinone Sodium Injection on the basis of control group, 80 mg/time, once daily. Both groups were treated continuously for two weeks. Clinical efficacy of two groups was observed, and the frequency of premature ventricular beats, ST segment displacement time, ST segment depression distance, SV, CO, and RI before and after treatment were compared between two groups. Results After treatment, the total clinical effective rate of the observation group was 93.75%, which was significantly higher than 79.17% of the control group, the difference being statistically significant (P < 0.05). After treatment, the frequency of premature ventricular beats, ST segment descending time, and ST segment depression distance were significantly decreased in both groups (P < 0.05). The frequency of premature ventricular beats, ST segment downshift time and ST segment depression distance in the observation group were lower than those in the control group after treatment, with statistical significance (P < 0.05). After treatment, SV and CO in two groups were significantly increased, while RI was significantly decreased (P < 0.05). After treatment, SV and CO in the observation group were higher than those in the control group, while RI in the observation group was lower than those in the control group, with statistical significance (P < 0.05). Conclusion Sulfotanshinone Sodium Injection combined with amiodarone can improve the therapeutic efficacy of ventricular premature beat, improve hemodynamics, and the level of the electrocardiogram, it has security and good clinical value.

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