金線蓮來(lái)源于蘭科開(kāi)唇蘭屬植物金線蘭Anoectochilus roxburghii （Wall.）Lindl.，主要分布于中國(guó)福建、浙江、江西等地。金線蓮多糖作為其主要成分，具有抗糖尿病、保肝、抗炎和抗腫瘤等藥理作用，其主要通過(guò)抗氧化、調(diào)節(jié)脂質(zhì)代謝、調(diào)節(jié)機(jī)體免疫以及誘導(dǎo)細(xì)胞凋亡等發(fā)揮作用。就金線蓮多糖的上述藥理作用及作用機(jī)制的研究進(jìn)展進(jìn)行闡述，旨在為其后續(xù)的制劑開(kāi)發(fā)、臨床研究與應(yīng)用提供理論基礎(chǔ)及文獻(xiàn)依據(jù)。

Anoectochilus roxburghii (Wall.) Lindl. belongs to the orchids, which mainly distributed in Fujian, Zhejiang and Jiangxi provinces. Polysaccharides of Anoectochilus roxburghii is the main component of Anoectochilus roxburghii, which has the effect on the anti-diabetic, hepatoprotective, anti-inflammatory and anti-tumor, mainly through antioxidation, regulation of lipid metabolism, regulation of body immunity and induction of apoptosis. In the review, we summarized the progress of pharmacological action and mechanism of Anoectochilus roxburghii, to provide a theoretical basis and literature for the subsequent preparation development, clinical research and application of the valuable Chinese herb.

R285.5

福州市科技局社會(huì)發(fā)展項(xiàng)目（2019-SZ-42）；福州市感染性疾病醫(yī)學(xué)中心資助項(xiàng)目（2018080306）