[關(guān)鍵詞]
[摘要]
我國(guó)兒科藥品劑型較豐富,但是常用藥物種類及規(guī)格仍無(wú)法滿足日益增長(zhǎng)的用藥需求。綜述我國(guó)兒科藥品常用劑型種類及其應(yīng)用現(xiàn)狀,發(fā)現(xiàn)兒童常用藥物劑型有片劑、顆粒劑、注射劑等,口服劑型所面臨的主要問(wèn)題是口感差、用藥依從性低;非口服劑型用藥依從性相對(duì)較高,但兒童用產(chǎn)品較少,需大力開(kāi)發(fā)。針對(duì)各劑型研發(fā)所面臨的機(jī)遇及挑戰(zhàn),未來(lái)兒童用藥首選劑型仍是口服制劑,但是會(huì)向微片、微丸、分散片的形式發(fā)展。
[Key word]
[Abstract]
China's pediatric drug dosage form is relatively rich, but the types and specifications of commonly used medicines still cannot meet the increasing demand for medicines. The author reviewed the types of commonly used pediatric drugs and their application status in China, and found that the commonly used drug forms for children include tablets, granules, injections, etc. The main problems faced by oral dosage forms are poor taste and low medication compliance; the compliance of non-oral dosage forms medication is relatively high, but there are few products for children, which need to be developed vigorously. In view of the opportunities and challenges faced by the development of various dosage forms, the preferred dosage form for children's medicine in the future will still be oral preparations, but will develop into the form of microtablets, pellets, and dispersible tablets.
[中圖分類號(hào)]
R944.5
[基金項(xiàng)目]
山西省重點(diǎn)研發(fā)項(xiàng)目(201603D321028);山西省“四個(gè)一批”科技興醫(yī)創(chuàng)新計(jì)劃項(xiàng)目(2020SYS09);山西省醫(yī)學(xué)重點(diǎn)科研項(xiàng)目計(jì)劃重點(diǎn)攻關(guān)專項(xiàng)(2021XM32)