金花茶Camellia nitidissima為我國廣西地區(qū)的少數(shù)民族常用藥，具有清熱解毒、利尿消腫等功效。近年來，對于金花茶開展了大量的化學(xué)成分和藥理學(xué)研究，表明金花茶含有黃酮類化合物、多糖、皂苷等多種生物活性成分，該植物及其提取物具有抗腫瘤、抗炎、抗氧化、調(diào)血脂、降血糖、抗肥胖、降血壓、抗過敏、抗衰老等藥理作用。對金花茶化學(xué)成分和藥理研究進(jìn)展進(jìn)行了歸納總結(jié)，為更好地利用該植物和新藥研發(fā)提供理論參考。

Camellia nitidissima is common traditional ethnic medicine in Guangxi, which takes effect by clearing away heat and toxic materials and diuretic detumescence. In recent years, a great number of chemical, and pharmacological studies on Camellia nitidissima Chi have been carried out, primarily in China. Phytochemical investigations have shown that the plant contains a rich source of bioactive constituents, including flavonoids, polysaccharides, saponins, and other components. Pharmacological studies have demonstrated that Camellia nitidissima Chi possesses anti-tumour, anti-inflammatory, antioxidant, hypolipidemic effect, hypoglycemic, anti-obesity, hypotensive, anti-anaphylaxis, and anti-aging properties. The present paper presents an up-to-date overview of the chemical constituents and pharmacological effects of Camellia nitidissima Chi in order to explore the potential of this plant for drug development.

R285.5

國家中醫(yī)藥管理局國際合作司中醫(yī)藥國際合作專項(xiàng)（0610-2140NF020630）；廣西創(chuàng)新驅(qū)動(dòng)發(fā)展專項(xiàng)資金資助項(xiàng)目（桂科AA18118049-3） ；中國醫(yī)學(xué)科學(xué)院醫(yī)學(xué)與健康科技創(chuàng)新工程資助項(xiàng)目（2019-I2M-5-020）