[關(guān)鍵詞]
[摘要]
丹參Salvia miltiorrhiza作為臨床上常用的活血化瘀藥,其藥理作用廣泛,尤其在治療腦血管病上方面效果良好,其主要活性成分和制劑均具有良好的改善腦側(cè)支循環(huán)及促進(jìn)血管生成的藥理作用。通過(guò)對(duì)改善腦側(cè)支循環(huán)和血管生成的丹參活性成分(丹參素類(lèi)和丹參酮類(lèi))和丹參類(lèi)制劑(丹參注射劑如注射用丹參多酚酸、注射用丹參多酚酸鹽、丹紅注射液及口服制劑如復(fù)方丹參滴丸、復(fù)方丹參片、復(fù)方丹參顆粒等)的藥理作用進(jìn)行綜述,為臨床合理用藥以及與側(cè)支循環(huán)和血管生成相關(guān)的腦血管病治療提供依據(jù)。
[Key word]
[Abstract]
Salvia miltiorrhiza, is a common using clinical drug to invigorate the circulation of blood and dispersing blood stasis, has a wide range of pharmacological effects, especially effective in the treatment of cerebrovascular diseases, and its main active ingredients and preparations have good pharmacological effects on improving cerebral collateral circulation and promoting angiogenesis. By reviewing the pharmacological effects of the active ingredients, which to improve cerebral collateral circulation and angiogenesis (tanshinin and tanshinone) and salvia preparations (danshen injections such as Danshen Polyphenolic Acid for Injection, Danshen Polyphenolate for Injection, Danshen Injection and oral preparations such as compound Danshen Drop Pills, Compound Danshen Tablets, Compound Danshen Granules, etc.), this paper provides a basis for clinical rational drug using and the treatment of cerebrovascular diseases related to collateral circulation and angiogenesis.
[中圖分類(lèi)號(hào)]
[基金項(xiàng)目]