辣木葉來源于熱帶植物辣木Moringa oleifera，以葉入藥，具有良好的生理活性。現(xiàn)代研究顯示辣木葉含有豐富的黃酮、多糖、多酚、生物堿等功能成分，具有明確的抗氧化、抗菌、降糖、抗高脂血癥等藥理作用。辣木葉及其有效成分可能通過抑制脂質(zhì)過氧化、抑制胰脂肪酶活性、抑制α-葡萄糖苷酶活性、誘導(dǎo)棕色脂肪組織生成、提高膽汁酸結(jié)合能力等途徑達到抗高脂血癥作用。綜述辣木葉及其有效成分抗高脂血癥藥理作用的研究進展，以期為利用該藥用植物資源開發(fā)新藥提供依據(jù)。

Moringa oleifera leaves are derived from Moringa oleifera Lam. and used as medicine. Modern studies have shown that M. oleifera leaves are rich in functional components such as flavonoids, polysaccharides, polyphenols and alkaloids, and have defined pharmacological effects such as antioxidant, antibacterial, hypoglycemic and anti-hyperlipidemia. M. oleifera leaves and its active components may achieve the anti-hyperlipidemia effect by inhibiting lipid peroxidation, inhibiting the activity of pancreatic lipase, inhibiting the activity of α-glucosidase, inducing the formation of brown adipose tissue, and improving the bile acid binding ability. The research progress of the pharmacological effects of M. oleifera leaves and its active components on anti-hyperlipidemia are reviewed, in order to provide a basis for the development of new drugs for hyperlipidemia using the medicinal plant resources.

廣東省大學(xué)生創(chuàng)新創(chuàng)業(yè)訓(xùn)練計劃（S202210590113）；深圳市基礎(chǔ)研究面上項目（JCYJ20220531102208019）；深圳市藥學(xué)會醫(yī)院藥學(xué)研究基金（恒瑞基金）（SZ2022A25）；深圳大學(xué)聚徒＋學(xué)術(shù)項目（803-0000311684）