目的 分析中醫(yī)藥治療外感寒、熱及外寒內熱型咳嗽用藥特點，為臨床用藥提供參考。方法 通過查閱中醫(yī)古籍、中國學術期刊全文數(shù)據庫（CNKI）、萬方數(shù)據庫（Wanfang Data）、維普生物醫(yī)學數(shù)據庫（VIP）等平臺檢索篩選中藥治療風寒襲肺、風熱犯肺和外寒內熱型咳嗽的處方，使用中醫(yī)傳承輔助平臺（V2.5）分析3類證型處方中藥的藥物頻次、性味歸經、關聯(lián)規(guī)則分析。結果 風寒襲肺型咳嗽共包含處方263條，184味中藥，其中使用頻次較高的有甘草、杏仁、麻黃、桔梗、半夏、陳皮等中藥。風熱犯肺型咳嗽共包含處方314條，217味中藥，其中使用頻次較高的有甘草、杏仁、桔梗、黃芩、麻黃、桑白皮等藥物。外寒內熱型咳嗽共包含處方102條，有128味中藥，其中使用頻次較高的有甘草、杏仁、麻黃、黃芩、半夏、桔梗等藥物。結論 統(tǒng)計分析結果表明治療3類證型咳嗽多以解表藥、止咳化痰藥、理氣藥為主，藥性多溫、平，藥味辛、甘，歸入肺、脾經等。

Objective To analyze the characteristics of traditional Chinese medicine (TCM) medications used in the treatment of externally induced cold, heat and externally cold and internally heated coughs, and to provide a reference for clinical use of medications. Methods Searching and screening the prescriptions of traditional Chinese medicine for the treatment of wind-cold attacking the lungs, wind-heat attacking the lungs, and external-cold and internal-heat type of coughs by consulting ancient Chinese medical writings and books, platforms of China National Knowledge Infrastructure, Wanfang Data, VIP Database for Chinese Technical Periodicals, The frequency of drugs, medicinal flavor attribution, association rule analysis were analyzed using the Traditional Chinese Medicine Inheritance Support System (V2.5). Results Prescription for wind-cold-attacked lung-type cough contained 263 prescriptions and 184 Chinese herbal medicines, of which those used more frequently included Glycyrrhizae Radix et Rhizoma, Armeniacae Semen Amarum, Ephedrae Herba, Platycodon Radix, Pinelliae Rhizoma, Citri Reticulatae Pericarpium. Prescription for wind-heat-affected lung cough contained a total of 314 prescriptions and 217 Chinese herbal medicines, among which Glycyrrhizae Radix et Rhizoma, Armeniacae Semen Amarum, Platycodon Radix, Scutellariae Radix, Ephedrae Herba, and Mori Cortex were used more frequently. Prescription for the external cold and internal heat type of cough contained a total of 102 prescriptions with 128 Chinese herbal medicines, among which the more frequently used medicines were Glycyrrhizae Radix et Rhizoma, Armeniacae Semen Amarum, Ephedrae Herba, Scutellariae Radix, Pinelliae Rhizoma, Platycodon Radix. Conclusion Statistical analysis of the results showed that the treatment of the three types of cough is mostly based on diaphoretic, cough phlegm medicine, qi-regulating medicine, the nature of the medicine is mostly warm, flat, the taste of the medicine is pungent, sweet, and attributed to the lung and spleen meridians, etc., which provides a certain reference for the treatment of externally induced cold, heat, and externally chilled and internally heated coughs in TCM.

R28

安徽省科技重大專項計劃（202303a07020007）;廣西創(chuàng)新驅動發(fā)展專項資金資助項目（桂科A A 18118049-3）