生地黃Rehmannia glutinosa屬玄參科地黃屬多年生草本植物，有清熱涼血、養(yǎng)陰生津的功效，其所含化學成分有200余種，包括環(huán)烯醚萜類及環(huán)烯醚萜苷類、氨基酸類、紫羅蘭酮類、微量元素、苯乙醇苷類、糖類等，其中地黃多糖和梓醇是生地黃的主要活性成分，具有降血糖、抗衰老、增強免疫、抗腫瘤、神經系統(tǒng)保護、抗抑郁、抗炎、改善骨質疏松等藥理作用。主要對生地黃提取物及有效成分地黃多糖、梓醇的藥理作用進行全面綜述，以期為生地黃的藥品開發(fā)及臨床應用提供更多理論基礎與依據。

Rehmannia glutinosa is a perennial herb belonging to the genus Rehmannia in the family of Scrophulariaceae, which has the effect of clearing heat and cooling blood, nourishing yin and generating fluids, and contains more than 200 chemical components, including cyclic enol ether terpenes and cyclic enol ether terpene glycosides, amino acids, violet ketones, trace elements, phenyl glycosides, sugars, etc., among which, R. glutinosa polysaccharides and catalpol are the main active ingredients of R. glutinosa and have the effects such as hypoglycemia, anti-aging, enhancement of immunity, anti-tumor, neurological protection, antidepressant, anti-inflammatory, and improvement of osteoporosis. A comprehensive review of the pharmacological effects of R. glutinosa extracts and the active ingredients R. glutinosa polysaccharides and catalpol was carried out in order to provide more theoretical basis for the development of R. glutinosa and its clinical application.

R285.5

黑龍江省中醫(yī)藥科研項目（ZYW2023-063）