桑黃是一種應(yīng)用廣泛的藥用真菌?，F(xiàn)代研究表明桑黃的化學(xué)成分主要為多糖、酚酸、黃酮、萜類、甾體等，具有抗炎、抗腫瘤、鎮(zhèn)靜催眠、降血糖等多種藥理作用。基于桑黃化學(xué)成分和藥理作用的研究進(jìn)展，從物質(zhì)功效關(guān)聯(lián)性、有效性、特有性、可測(cè)性及傳遞性，對(duì)桑黃質(zhì)量標(biāo)志物（Q-Marker）進(jìn)行推測(cè)，預(yù)測(cè)麥角甾醇、phellibaumin D及包括桑黃素、花旗松素等在內(nèi)的黃酮類成分可能為桑黃Q-Marker的候選成分。

Phellinus igniarius (Sanghuang) is a widely used medicinal fungus. Modern research indicates that its chemical components primarily include polysaccharides, phenolic acids, flavonoids, terpenoids, steroids, and others, which exhibit diverse pharmacological activities such as anti-inflammatory, anti-tumor, sedative-hypnotic, and hypoglycemic effects. Based on advances in the study of its chemical composition and pharmacological properties, this paper evaluates potential quality markers (Q-Marker) for Sanghuang by analyzing substance-efficacy correlations, effectiveness, specificity, measurability, and transferability. It is hypothesized that ergosterol, phellibaumin D, and flavonoid constituents such as sanghuangin and taxifolin may serve as candidate Q-Marker for Sanghuang.

R969.2

國(guó)家自然科學(xué)基金資助項(xiàng)目（82274091）