從紫花高烏頭根的苯提取物中分離到3個二萜生物堿,經理化性質和光譜分析分別鑒定為lappaconitine(I)、ranaconitine(Ⅱ)和 septentriodine(Ⅲ)。化合物 Ⅱ和Ⅲ為首次從該植物中分離到,其中Ⅱ含量最高,根據文獻報道Ⅰ和Ⅱ是抗心率失常和鎮(zhèn)痛作用的有效成分。

Three diterpenoid alkaloids were obtained from the C_6H_6 extract of the root of Aconitum excelsum. Their structures were identified on the basis of spectral data (MS, IR, ~1HNMR, ~(13)CNMR, DEPT) and physico-chemical properties as lappaconitine (I), ranaconitine (Ⅱ) and septentriodine（Ⅲ). Compounds Ⅱand Ⅲ were obtained for the first time from this plant. Compounds Ⅰ and Ⅱ exhibited analgesic and antiarrhythmic activities, as documented in literature reports.

國家自然科學基金39560087