以銀杏葉浸膏EGb761為原料,通過預(yù)處理、制備色譜和重結(jié)晶過程,得到純度達98%以上的銀杏內(nèi)酯A、B和白果內(nèi)酯純品。建立了一種較簡單的分離和純化銀杏內(nèi)酯A、B和白果內(nèi)酯的方法

A simple method for the isolation and purification of ginkgolide A, B and bilobalide (ginkgo terpene trialctone) was developed A commercially available extract of leaves of Ginkgo biloba L. containing 6% ginkgo terpene trilactone was used as the raw material After partition in EtOAc, the enriched extract was separated to give individual terpenes by preparative liquid chromatography Ginkgolide A, B and bilobalide could be isolated with high purity by recrystallizing in MeOH H 2O

天津市自然科學(xué)基金項目!(No.9936 0 6 911)