目的 建立爐甘石生品及炮制品的X射線衍射（XRD）指紋圖譜；比較不同炮制方法對藥材主要成分的影響；測定炮制品中ZnO含量。方法 采用XRD法對10批爐甘石生品及炮制品進行分析，分別建立了生品及炮制品的指紋圖譜；對6種不同炮制方法進行比較；運用K值法測定了炮制品中ZnO的含量。結(jié)果 分別建立了爐甘石生品和炮制品的XRD指紋圖譜，其中生品XRD指紋圖譜有23個共有峰，炮制品XRD指紋圖譜有10個共有峰，經(jīng)煅燒炮制之后生品的ZnCO₃特征峰轉(zhuǎn)變?yōu)閆nO的特征峰；煅燒炮制品中ZnO的含量均超過56%。結(jié)論 XRD指紋圖譜可用于爐甘石生品及炮制品的鑒定與分析，為爐甘石生品及炮制品的質(zhì)量評價提供了新的可靠方法。

Objective To establish X-ray diffraction (XRD) fingerprint of Calamina and its processed products, compare the effects of different processing methods on the main components of medicinal materials and determine the content of ZnO in the processed products. Methods XRD was used to analyze 10 batches of Calamina and its processed products, and fingerprints of Calamina and its processed products were established respectively. Six different processing methods were compared, and the content of ZnO in all processed products was determined by K value method. Results Fingerprints of Calamina and its processed products were preliminarily established. There were 23 common peaks in the fingerprints of Calamina, and there were 10 common peaks in the fingerprints of its processed products. After calcination, the ZnCO₃ characteristic peak of the raw material was transformed into the characteristic peak of ZnO; The content of ZnO in the calcined product exceeded 56%. Conclusion XRD fingerprints could be used for the identification and analysis of Calamina and its processed products. The new and reliable method was provided for quality evaluation of Calamina and its processed products.

R286.02

國家“十二五”科技支撐計劃（2012BAI27B07）；西南民族大學中央高?；究蒲袠I(yè)務費資助（2020NYB34）