中醫(yī)藥是中華民族幾千年實(shí)踐經(jīng)驗(yàn)的總結(jié)，在重大慢性疾病、新發(fā)突發(fā)傳染病等方面表現(xiàn)出巨大潛力和良好的治療效果，中藥是先導(dǎo)化合物發(fā)現(xiàn)的巨大寶庫，其數(shù)據(jù)庫種類繁多，如中藥化學(xué)數(shù)據(jù)庫、 中藥系統(tǒng)藥理學(xué)數(shù)據(jù)庫與分析平臺、TCMBank 數(shù)據(jù)庫等。隨著人工智能技術(shù)的飛速發(fā)展，已進(jìn)入大數(shù)據(jù)時(shí)代，人工智能與中醫(yī)藥深度融合推動(dòng)了中藥數(shù)據(jù)庫的發(fā)展。中藥信息標(biāo)準(zhǔn)化、 數(shù)據(jù)分析智能化是中醫(yī)藥現(xiàn)代化發(fā)展的必由之路，開辟了中醫(yī)藥科技創(chuàng)新賽道，是推動(dòng)中醫(yī)藥產(chǎn)業(yè)高質(zhì)量發(fā)展的強(qiáng)大引擎。通過對中藥數(shù)據(jù)庫的研究進(jìn)展進(jìn)行綜述，并對數(shù)據(jù)庫的應(yīng)用進(jìn)行展望，為推動(dòng)中藥數(shù)據(jù)庫在人工智能支持下的創(chuàng)新升級提供參考，助力中藥產(chǎn)業(yè)的現(xiàn)代化發(fā)展。

Traditional Chinese medicine (TCM) represents a synthesis of millennia of practical experience of the Chinese nation, showing great potential in the treatment of major chronic diseases and emerging infectious diseases. TCM serves as a vast treasure trove for the discovery of potential lead compounds, with a wide variety of databases, such as Traditional Chinese Medicines Database (TCMD), Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP), TCMBank database, and so on. With the rapid development of artificial intelligence (AI) technology, we have entered the big data era. The deep integration of AI with TCM has facilitated development of TCM databases. The standardization of TCM information and intelligent data analysis are critical approaches for the modernization of TCM, opening new avenues for technological innovation in TCM and serving as a powerful engine for highquality development of TCM industry. This review discusses the progress in the research on TCM databases and their prospective applications. It aims to provide a reference for innovative upgrade of TCM databases supported by AI and ultimately facilitating the modernization and development of TCM industry.

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國家自然科學(xué)基金資助項(xiàng)目(82104372);現(xiàn)代中醫(yī)藥海河實(shí)驗(yàn)室科技項(xiàng)目(22HHZYJC00007,22HHZYSS00007)