三七 Notoginseng Radix et Rhizoma 是藥食兩用的名貴中藥之一，其使用歷史悠久，療效顯著。但市場(chǎng)上的三七質(zhì)量參差不齊，甚至存在以次充好和摻偽、摻雜等現(xiàn)象。此外，三七的外源性農(nóng)藥、重金屬與有害元素等的污染也不容忽視。從有效性和安全性 2 個(gè)方面入手，對(duì)基于有效成分的三七真?zhèn)舞b別和內(nèi)在質(zhì)量評(píng)價(jià)及外源性有毒有害污染物檢測(cè)等研究現(xiàn)狀進(jìn)行綜述，為更科學(xué)、合理的三七整體質(zhì)量評(píng)價(jià)提供參考，為保障三七的藥用價(jià)值和控制食藥用安全性風(fēng)險(xiǎn)奠定基礎(chǔ)。

Sanqi (Notoginseng Radix et Rhizoma) is one of the valuable traditional Chinese medicines with dual purposes as both food and medicine. It has a long history of use and remarkable therapeutic effects. However, the quality of Notoginseng Radix et Rhizoma varies in markets. There are even illegal behaviors such as substitution, adulteration, and mixing with inferior materials. In addition, the pollution of exogenous pesticide residues, heavy metals and harmful elements in Notoginseng Radix et Rhizoma cannot be ignored. From the perspectives of effectiveness and safety, this article reviews research progress on authenticity identification based on active ingredients and intrinsic quality evaluation of Notoginseng Radix et Rhizoma, as well as detection and determination of exogenous toxic and harmful pollutants in Notoginseng Radix et Rhizoma. It would provide a reference for a more scientific and reasonable holistic quality evaluation of Notoginseng Radix et Rhizoma, and lay a foundation for ensuring its medicinal value and controlling the safety risk for food and medicine use.

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國家自然科學(xué)基金資助項(xiàng)目(82104390);國家藥品監(jiān)督管理局中藥質(zhì)量控制重點(diǎn)實(shí)驗(yàn)室開放研究課題(2023-ZY-01);上海市中藥和保健食品品質(zhì)與安全檢測(cè)專業(yè)技術(shù)服務(wù)平臺(tái)(21DZ2290200)